SCCS/1663/24 15 NOAEL rows Safety conclusion

Vetiveria zizanioides ext., acetylated, Acetylated Vetiver Oil (AVO) - sprayable

Structured SCCS opinion summary generated from source-matched D1 rows for SCCS/1663/24.

Opinion Number
SCCS/1663/24
NOAEL Rows
15
Substances Covered
2

Substance(s) Covered

Vetiveria zizanioides ext., acetylated Acetylated Vetiver Oil (AVO) - sprayable

NOAEL Values Extracted from This Opinion

Substance Endpoint Value Study Source
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 11 Not recorded
Regulatory source
p.30
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 13 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 2018 Not recorded
Regulatory source
p.30
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 NOAEL 58330 Not recorded
Regulatory source
p.31
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 repeated dose toxicity 350 mg / kg bw repeated dose toxicity
oral
Sub-chronic
Regulatory source
p.17
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 repeated dose toxicity 350 mg / kg bw repeated dose toxicity
oral
Sub-chronic
Regulatory source
p.17
SCCS Opinion
Vetiveria zizanioides ext., acetylated
84082-84-8
 sensitisation 350 mg/kg bw sensitisation
human
inhalation
Regulatory source
p.32
SCCS Opinion

Safety Conclusion

sccs_opinions Max 0.9% fragrance pump sprays; 0.05% deodorant aerosol sprays; 0.1% hairsprays and body lotion sprays
Safe with restrictions in sprayable cosmetic products (with 1% alpha-tocopherol)

Key concerns: Inhalation toxicity; complex UVCB substance; submission IV (sprayable extension to SCCS/1599/18)

Opinion date: 25 October 2024

safety_opinions
unknown

Opinion date: 25 October 2024

Source Citation

Primary source https://health.ec.europa.eu/scientific-committees/scientific-committee-consumer-safety-sccs/sccs-opinions_en