SCCS/1686/25 4 NOAEL rows Safety conclusion

Thiomersal, Thiomersal and Phenylmercuric salts, Unknown

Structured SCCS opinion summary generated from source-matched D1 rows for SCCS/1686/25.

Opinion Number
SCCS/1686/25
NOAEL Rows
4
Substances Covered
3

Substance(s) Covered

Thiomersal Thiomersal and Phenylmercuric salts Unknown

NOAEL Values Extracted from This Opinion

Substance Endpoint Value Study Source
Thiomersal
54-64-8
 NOAEL 1686 NOAEL study
rat
oral
16 weeks
SCCS Opinion
p.19
SCCS Opinion
Thiomersal
54-64-8
 NOAEL 1686 NOAEL study
rat
oral
16 weeks
SCCS Opinion
p.19
SCCS Opinion
Thiomersal
54-64-8
 NOAEL 1686 NOAEL study
rat
oral
16 weeks
SCCS Opinion
p.19
SCCS Opinion
Thiomersal
54-64-8
 NOAEL 1686 NOAEL study
rat
oral
16 weeks
SCCS Opinion
p.19
SCCS Opinion

Safety Conclusion

sccs_opinions
Not safe — not safe as preservatives in eye cosmetic products at currently permitted levels

Key concerns: Renal toxicity (MoS<100 at 0.007%); genotoxicity unresolved; organo-mercury compounds with systemic absorption risk

Opinion date: 2 February 2026

safety_opinions eye area Max 0.007
unknown

Opinion date: 2 February 2026

Source Citation

Primary source https://health.ec.europa.eu/scientific-committees/scientific-committee-consumer-safety-sccs/sccs-opinions_en