EFSA toxicology reference values

Phenol

SOURCE efsa openfoodtox 3 0 export repository

Phenol (CAS 108-95-2). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.

Phenol is a cannabis analyte contaminant represented in the cannabis public dataset.

CAS 108-95-2 Cannabis Analyte

Substance Identity

Analyte identity and classification used for this cannabis substance page.

SOURCE efsa substances
Analyte name
Phenol
CAS number
108-95-2
Contaminant class
Cannabis Analyte

Contaminant Class Badge

Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.

SOURCE State Cannabis Regulations
Cannabis Analyte Cannabis contaminant class used to group state testing rows.

Dataset Snapshot

Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.

SOURCE cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
108-95-2

EFSA Substance Identity

EFSA substance identity rows matched by chemical name or CAS.

SOURCE efsa openfoodtox 3 0 export repository
Phenol
CAS 108-95-2 / mono-constituent substance
C6H6O / 2 dossier(s)

EFSA Reference Values

Reference values from efsa_reference_values_v2 for toxicology and food-safety context.

SOURCE efsa openfoodtox 3 0 export repository
DescriptorValuePopulationEndpointBody
TDI 0.5 mg/kg bw/day consumers ab401bd3-c897-45a4-99a9-5ed13e943295 -
TTC Cramer Class I 30 µg/kg bw/day consumers - -
MOE 10,000 other: consumers 2270774f-cc58-4b2f-b35c-6decb0609f0e -

EFSA Study Results

Endpoint-level study rows from efsa_study_results matched to this substance.

SOURCE efsa openfoodtox 3 0 export repository
EndpointSpeciesRouteEffectAssessment
short-term repeated dose toxicity: oral mouse oral: drinking water 1.8 other: -
toxicity to reproduction: other studies rat oral: gavage 52 mg/kg bw/day -
toxicity to reproduction: other studies rat oral: gavage 60 other: -
toxicity to reproduction: other studies rat oral: gavage 120 other: -
Carcinogenicity_EU_PPP - - - The German Federal Institute for Risk Assessment (BfR) asks the European Food Safety Authority to provide a scientific opinion on the re-evaluation of the tolerable daily intake (TDI) for phenol of 1.5 mg/kg bw/day set by the SCF in 1984 (EC, 1987).
Carcinogenicity_EU_PPP - - - The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The Panel has considered three substances in the JECFA flavouring group of phenol and phenol derivatives. The Panel concluded that no corresponding Flavouring Group Evaluation (FGE) is available. Considering the EU Risk Assessment Report on phenol, the Panel concluded that the available data do not preclude the evaluation of phenol and its two esters, phenol acetate and phenyl, through the Procedure. However, the Panel did not fully agree with the application of the Procedure as performed by the JECFA for the three substances considered in this FGE. Due to the possible formation of toxic metabolites like hydroquinones and quinones, the Panel considered that phenol and its two esters could not be predicted to be metabolised to innocuous products.
Genetic Toxicity - - - The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The Panel has considered three substances in the JECFA flavouring group of phenol and phenol derivatives. The Panel concluded that no corresponding Flavouring Group Evaluation (FGE) is available. Considering the EU Risk Assessment Report on phenol, the Panel concluded that the available data do not preclude the evaluation of phenol and its two esters, phenol acetate and phenyl, through the Procedure. However, the Panel did not fully agree with the application of the Procedure as performed by the JECFA for the three substances considered in this FGE. Due to the possible formation of toxic metabolites like hydroquinones and quinones, the Panel considered that phenol and its two esters could not be predicted to be metabolised to innocuous products.
Genetic Toxicity - - - The German Federal Institute for Risk Assessment (BfR) asks the European Food Safety Authority to provide a scientific opinion on the re-evaluation of the tolerable daily intake (TDI) for phenol of 1.5 mg/kg bw/day set by the SCF in 1984 (EC, 1987).

Frequently Asked Questions

FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.

SOURCE page FAQ dataset

What is the regulatory limit for Phenol in cannabis?

Phenol does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.

Which states test for Phenol?

Phenol does not have state-level cannabis testing rows in the fetched page data.

What are the EFSA reference values for Phenol?

Phenol has 3 EFSA OpenFoodTox reference value rows in the cannabis database, including TDI, TTC Cramer Class I, MOE.

Is Phenol also regulated in cosmetics or food?

Phenol has a cosmetics ingredient cross-reference with EU status restricted. EFSA food/toxicology context is available on this page.