EFSA toxicology reference values
2,6,6-Trimethylcyclohex-2-en-1,4-dione
SOURCE
efsa openfoodtox 3 0 export repository
2,6,6-Trimethylcyclohex-2-en-1,4-dione (CAS 1125-21-9). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
2,6,6-Trimethylcyclohex-2-en-1,4-dione is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 1125-21-9
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
efsa substances
Analyte name
2,6,6-Trimethylcyclohex-2-en-1,4-dione
CAS number
1125-21-9
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
SOURCE
State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
SOURCE
cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
1125-21-9
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
efsa openfoodtox 3 0 export repository
2,6,6-Trimethylcyclohex-2-en-1,4-dione
CAS 1125-21-9 / mono-constituent substance
C9H12O2 / 6 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
efsa openfoodtox 3 0 export repository
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| MSI/FC | 0.3 mg/kg | other: | - | - |
| MSI/FC | 0.3 mg/kg | other: | - | - |
| MSI/FC | 0.5 mg/kg | cattle for fattening | - | - |
| MSI/FC | 0.5 mg/kg | other: | - | - |
| MSI/FC | 0.5 mg/kg | other: | - | - |
| MSI/FC | 0.5 mg/kg | salmon | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | other: |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | other: |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| margin of safety | - | consumers | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
efsa openfoodtox 3 0 export repository
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel was asked to evaluate flavouring substances using the procedure referred to in Commission Regulation EC No 1565/2000 (hereafter 'the Procedure'). The Flavouring Group Evaluation (FGE) 213 concerns 26 substances, corresponding to subgroup 2.7 of FGE.19. Twenty-three of the substances are alpha,beta-unsaturated alicyclic ketones [Flavour Information System (FL)-nos: 07.008, 07.010, 07.014, 07.041, 07.047, 07.056, 07.057, 07.075, 07.076, 07.080, 07.083, 07.089, 07.108, 07.109, 07.117, 07.118, 07.119, 07.120, 07.127, 07.136, 07.168, 07.200 and 07.224] and three are precursors for such ketones [FL-nos: 02.106, 09.305 and 09.525]. |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 213 (FGE.213) concerns 26 substances. The 26 substances correspond to subgroup 2.7 of FGE.19. Twenty-three of the substances are alpha,beta-unsaturated alicyclic ketones [FL-no: 07.008, 07.010, 07.014, 07.041, 07.047, 07.056, 07.057, 07.075, 07.076, 07.080, 07.083, 07.089, 07.108, 07.109, 07.117, 07.118, 07.119, 07.120, 07.127, 07.136, 07.168, 07.200 and 16.044] and three are precursors for such ketones [FL-no: 02.106, 09.305 and 09.525]. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 11 compounds belonging to chemical group 10. They are currently authorised as flavours in food. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel is asked to evaluate flavouring substances using the procedure as referred to in the Commission Regulation EC No 1565/2000. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission,the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 21 flavouring substances in the Flavouring Group Evaluation (FGE) 9, Revision 5 (FGE.09Rev5), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These flavouring substances belong to chemical group 8, 25 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 22 flavouring substances in the Flavouring Group Evaluation (FGE) 9, Revision 6 (FGE.09Rev6), using the Procedure referred to in Commission Regulation (EC) No 1565/2000 "(hereinafter 'the Procedure')". These flavouring substances belong to chemical groups 8, 25 and 30 of Annex I of the Commission Regulation (EC) No 1565/2000. The present revision of FGE.09, FGE.09Rev6, includes the assessment of one additional candidate substance, trans-3-methyl-2-(2-pentenyl)-2-cyclopenten-1-one [FL-no: 07.219], which was not included in FGE.09Rev5. This substance is an alpha,beta-unsaturated carbonyl, for which concern for genotoxicity was ruled out in FGE.212Rev3. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 22 flavouring substances in the Flavouring Group Evaluation (FGE) 9, Revision 6 (FGE.09Rev6), using the Procedure referred to in Commission Regulation (EC) No 1565/2000 "(hereinafter 'the Procedure')". These flavouring substances belong to chemical groups 8, 25 and 30 of Annex I of the Commission Regulation (EC) No 1565/2000. The present revision of FGE.09, FGE.09Rev6, includes the assessment of one additional candidate substance, trans-3-methyl-2-(2-pentenyl)-2-cyclopenten-1-one [FL-no: 07.219], which was not included in FGE.09Rev5. This substance is an alpha,beta-unsaturated carbonyl, for which concern for genotoxicity was ruled out in FGE.212Rev3. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission,the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 21 flavouring substances in the Flavouring Group Evaluation (FGE) 9, Revision 5 (FGE.09Rev5), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These flavouring substances belong to chemical group 8, 25 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel was asked to evaluate flavouring substances using the procedure referred to in Commission Regulation EC No 1565/2000 (hereafter 'the Procedure'). The Flavouring Group Evaluation (FGE) 213 concerns 26 substances, corresponding to subgroup 2.7 of FGE.19. Twenty-three of the substances are alpha,beta-unsaturated alicyclic ketones [Flavour Information System (FL)-nos: 07.008, 07.010, 07.014, 07.041, 07.047, 07.056, 07.057, 07.075, 07.076, 07.080, 07.083, 07.089, 07.108, 07.109, 07.117, 07.118, 07.119, 07.120, 07.127, 07.136, 07.168, 07.200 and 07.224] and three are precursors for such ketones [FL-nos: 02.106, 09.305 and 09.525]. |
| Genetic Toxicity | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 213 (FGE.213) concerns 26 substances. The 26 substances correspond to subgroup 2.7 of FGE.19. Twenty-three of the substances are alpha,beta-unsaturated alicyclic ketones [FL-no: 07.008, 07.010, 07.014, 07.041, 07.047, 07.056, 07.057, 07.075, 07.076, 07.080, 07.083, 07.089, 07.108, 07.109, 07.117, 07.118, 07.119, 07.120, 07.127, 07.136, 07.168, 07.200 and 16.044] and three are precursors for such ketones [FL-no: 02.106, 09.305 and 09.525]. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 11 compounds belonging to chemical group 10. They are currently authorised as flavours in food. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel is asked to evaluate flavouring substances using the procedure as referred to in the Commission Regulation EC No 1565/2000. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
SOURCE
core public cross-reference
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
SOURCE
page FAQ dataset
What is the regulatory limit for 2,6,6-Trimethylcyclohex-2-en-1,4-dione in cannabis?
2,6,6-Trimethylcyclohex-2-en-1,4-dione does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 2,6,6-Trimethylcyclohex-2-en-1,4-dione?
2,6,6-Trimethylcyclohex-2-en-1,4-dione does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 2,6,6-Trimethylcyclohex-2-en-1,4-dione?
2,6,6-Trimethylcyclohex-2-en-1,4-dione has 12 EFSA OpenFoodTox reference value rows in the cannabis database, including MSI/FC, TTC Cramer Class II, margin of safety.
Is 2,6,6-Trimethylcyclohex-2-en-1,4-dione also regulated in cosmetics or food?
2,6,6-Trimethylcyclohex-2-en-1,4-dione has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.