EFSA toxicology reference values
L-Histidine
L-Histidine (CAS 71-00-1). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
L-Histidine is a cannabis analyte contaminant represented in the cannabis public dataset.
Substance Identity
Analyte identity and classification used for this cannabis substance page.
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| TTC Cramer Class III | 1.5 µg/kg bw/day | consumers | - | - |
| margin of safety | - | other: | - | - |
| margin of safety | - | other: | - | - |
| margin of safety | - | other: | - | - |
| margin of safety | - | consumers | - | - |
| margin of safety | - | consumers | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns 19 amino acids and related substances evaluated by the JECFA (63rd meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of nine structurally related amino acids from chemical group 34 evaluated by EFSA in Flavouring Group Evaluation 26, Revision 1 (FGE.26Rev1). |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 20 compounds belonging to chemical group (CG) 34 (amino acids), when used as flavourings for all animal species. All 20 additives are currently authorised for use as flavours in food and are ubiquitous in nature. The FEEDAP Panel was unable to perform an assessment of D,L-valine owing to the lack of data on the purity of the compound. Regulation (EC) No 1831/2003 establishes the rules governing the Community authorisation of additives for use in animal nutrition. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns 19 amino acids and related substances evaluated by the JECFA (63rd meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of nine structurally related amino acids from chemical group 34 evaluated by EFSA in Flavouring Group Evaluation 26, Revision 1 (FGE.26Rev1). |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 20 compounds belonging to chemical group (CG) 34 (amino acids), when used as flavourings for all animal species. All 20 additives are currently authorised for use as flavours in food and are ubiquitous in nature. The FEEDAP Panel was unable to perform an assessment of D,L-valine owing to the lack of data on the purity of the compound. Regulation (EC) No 1831/2003 establishes the rules governing the Community authorisation of additives for use in animal nutrition. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
What is the regulatory limit for L-Histidine in cannabis?
L-Histidine does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for L-Histidine?
L-Histidine does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for L-Histidine?
L-Histidine has 6 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class III, margin of safety.
Is L-Histidine also regulated in cosmetics or food?
L-Histidine has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.