What is the NOAEL for Manganese(II) sulfate monohydrate?
Manganese(II) sulfate monohydrate has 23 NOAEL studies in the database. The lowest reported value is W00LYS4T26 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Manganese(II) sulfate monohydrate
Also known as: Manganese sulfate (MnSO4) monohydrate, Manganese sulfate monohydrate, Manganous sulfate monohydrate, manganese(2+) sulfate monohydrate, Sulfuric acid, manganese(2+) salt, hydrate (1:1:1) (+9 more)
CAS 10034-96-5
Manganese(II) sulfate monohydrate (CAS 10034-96-5) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC.
Cross-Vertical Regulatory Divergence
Manganese(II) sulfate monohydrate is classified GHS Danger (H341, H302, H318, H372, H360, H373, H411) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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NOAEL studies
NOAEL studies
23
SOURCE
Chemical inventory jurisdictions
Regulatory lists
0
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
Manganese(II) sulfate monohydrate
CAS Number
10034-96-5
Molecular Formula
Mn.H2O4S.H2O
InChI Key
ISPYRSDWRDQNSW-UHFFFAOYSA-L
Monoisotopic Mass
170.915988
Synonyms
Manganese sulfate (MnSO4) monohydrateManganese sulfate monohydrateManganous sulfate monohydratemanganese(2+) sulfate monohydrateSulfuric acid, manganese(2+) salt, hydrate (1:1:1)Sulfuric acid, manganese(2+) salt (1:1), monohydrateManganese mesosulfate (MnSO4.H2O)Manganese monosulfate monohydrateSulfuric acid manganese salt (1:1) monohydrateUNII-W00LYS4T26Manganese sulfate hydrateMnSO4.H2O
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
WHO/JECFA
1 records
| Field | Value |
|---|---|
| GHS Signal Word | WARNING |
| GHS Hazard Statements | Causes serious eye irritation May cause damage to organs through prolonged or repeated exposure Toxic to aquatic life with long lasting effects |
| Short-term Effects | The substance is irritating to the eyes. |
| Long-term Effects | The substance may have effects on the central nervous system. Animal tests show that this substance possibly causes toxicity to human reproduction or development. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 23 of 23 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| W00LYS4T26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.01 | mg/m3 | LEL | inhalation | Rat | ECHA |
| >=0.06 | mg/m3 | LEL | inhalation | Monkey | ECHA |
| <=0.1 | mg/m3 | LEL | inhalation | Rat | ECHA |
| >=0.3 | mg/m3 | LEL | inhalation | Monkey | ECHA |
| =0.5 | mg/m3 | LEL | inhalation | Rat | ECHA |
| =1.5 | mg/m3 | LEL | inhalation | Monkey | ECHA |
| =72.8 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =83.7 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =230 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =618.5 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =727.7 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =925 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| =1700 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =2000 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =4925 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| =9850 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| <110 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB HESS |
| <115 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB HESS |
| 1500 | ppm | POLY-3 lowest dose | Dosed feed | Mouse | NTP ICE cancer |
| 1.500e+4 | ppm | POLY-3 lowest dose | Dosed feed | Mouse | NTP ICE cancer |
| 1.500e+4 | ppm | Top dose | Dosed feed | Rat | NTP ICE cancer |
Showing 23 of 23 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
mineral
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is Manganese(II) sulfate monohydrate used in cosmetics?
Yes, Manganese(II) sulfate monohydrate is also indexed as a cosmetic ingredient under the name Manganese Sulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Manganese(II) sulfate monohydrate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Manganese(II) sulfate monohydrate have different safety status in cosmetics vs industrial chemicals?
Manganese(II) sulfate monohydrate is classified GHS Danger (H341, H302, H318, H372, H360, H373, H411) in the chemicals database but is allowed in EU cosmetics.
Is Manganese(II) sulfate monohydrate used outside industrial chemicals?
Manganese(II) sulfate monohydrate also appears in cosmetics, cannabis databases.