What is the NOAEL for Hydroxylamine sulfate (2:1)?
Hydroxylamine sulfate (2:1) has 15 NOAEL studies in the database. The lowest reported value is 0.008 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Hydroxylamine sulfate (2:1)
Also known as: EINECS 233-118-8, UNII-49KP498D4O
CAS 10039-54-0
Hydroxylamine sulfate (2:1) (CAS 10039-54-0) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Hydroxylamine sulfate (2:1) is classified GHS Danger (H290, H302, H312, H315, H317, H319, H351, H373) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
15
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Hydroxylamine sulfate (2:1)
CAS Number
10039-54-0
DTXSID
DTXSID2025424
Molecular Formula
2H4NO.H2O4S
InChI Key
VGYYSIDKAKXZEE-UHFFFAOYSA-L
Monoisotopic Mass
166.025957
Synonyms
EINECS 233-118-8UNII-49KP498D4O
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes and skin. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. |
| Long-term Effects | Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in anaemia. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
7 records
AntioxidantChemical reaction regulatorUV stabilizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 15 of 15 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 210 | min | Breakthrough Time | Dermal | - | NTP_ICE_skin_irritation |
| =0.008 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 49KP498D4O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 49KP498D4O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 49KP498D4O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 49KP498D4O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | unitless | GHS classification | Dermal | Rabbit | NTP_ICE_skin_irritation |
| =0.2 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =0.4 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >0.9 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =3 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=20 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=21 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =25 | ppm | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =100 | ppm | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 15 of 15 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Bis(hydroxylammonium) sulphate | 233-118-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Frequently Asked Questions
What regulatory lists include Hydroxylamine sulfate (2:1)?
Hydroxylamine sulfate (2:1) appears on 1 regulatory/inventory list including Indirect additives food contact (10/2018). Source: EPA CPDat.
Is Hydroxylamine sulfate (2:1) used in cosmetics?
Yes, Hydroxylamine sulfate (2:1) is also indexed as a cosmetic ingredient under the name Hydroxylamine Sulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hydroxylamine sulfate (2:1) come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Hydroxylamine sulfate (2:1) have different safety status in cosmetics vs industrial chemicals?
Hydroxylamine sulfate (2:1) is classified GHS Danger (H290, H302, H312, H315, H317, H319, H351, H373) in the chemicals database but is allowed in EU cosmetics.
Is Hydroxylamine sulfate (2:1) used outside industrial chemicals?
Hydroxylamine sulfate (2:1) also appears in cosmetics databases.