Also known as: UNII-639H4QR04O, 1-gamma-Hydroxypropylamino-2-nitro-4-bis(beta-hydroxyethyl)aminobenzene, 1-Propanol, 3-((4-(bis(2-hydroxyethyl)amino)-2-nitrophenyl)amino)-, HC Violet 2, Imexine FAG
CAS 104226-19-9
HC Violet no. 2 (CAS 104226-19-9) is a chemical substance with GHS signal word Warning; key hazard signal: H317; H412. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, SCCS, ECHA REACH.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Skin Sens. 1; Aquatic Chronic 3 | H317; H412 | GHS07 | Warning |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care; restricted | European Commission | CosIng |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 50 | mg/kg bw/d | - | - | - | Regulatory source |
| 2500 | mg/kg bw/d | - | oral | human | Regulatory source |
| 639H4QR04O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 50 | mg/kg bw/day | LOAEL | oral | rat | COSMOS DB |
| =50 | mg/kg bw/d | NOAEL | - | - | SCCS Opinion |
| =50 | mg/kg bw | NOAEL | oral | rat | SCCS Opinion |
| =2500 | mg/kg bw/d | NOAEL | oral | human | SCCS Opinion |
| =50 | mg/kg bw | dermal absorption | oral | rat | Regulatory source |
| 50 | mg/kg bw/d | dermal absorption | dermal | mouse | Regulatory source |
Showing 9 of 9 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-((4-(bis(2-hydroxyethyl)amino)-2-nitrophenyl)amino)-1-propanol | 410-910-3 | ECHA overview → |
EU Scientific Committee opinions tied to the matched substance.
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCP/1081/07 | 2 October 2007 | safe | 0.3% | secondary amine; nitrosamine <50ppb; sensitisation not excluded |
Same-CAS cosmetic ingredient record for cross-vertical context.
HC Violet no. 2 (CAS 104226-19-9) is classified under EU CLP Annex VI as Skin Sens. 1; Aquatic Chronic 3 with signal word Warning. Hazard statements: H317; H412. Source: EU CLP Annex VI (ECHA).
HC Violet no. 2 has 9 NOAEL studies in the database. The lowest reported value is 50 mg/kg bw/d. Source: Regulatory source.
HC Violet no. 2 appears on 2 regulatory/inventory lists including Europe; Personal care; restricted, children; Europe; Personal care. Source: EPA CPDat.
Yes, HC Violet no. 2 is also indexed as a cosmetic ingredient under the name HC Violet No. 2. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
HC Violet no. 2 also appears in cosmetics databases.