REACH Registered Cosmetic Ingredient

Gamma-Heptalactone

Also known as: (+/-)-4-Heptanolide, Heptan-4-olide, 1,4-Heptanolide, 2(3H)-Furanone, dihydro-5-propyl-, 4-Hydroxyheptanoic acid, gamma-lactone (+14 more)

CAS 105-21-5

Gamma-Heptalactone (CAS 105-21-5) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for gamma-Heptalactone →

SOURCE NOAEL studies
NOAEL studies
0
SOURCE Chemical inventory jurisdictions
Regulatory lists
4
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 24 fields
Name
Gamma-Heptalactone
CAS Number
105-21-5
Molecular Formula
C7H12O2
InChI Key
VLSVVMPLPMNWBH-UHFFFAOYSA-N
Monoisotopic Mass
128.08373
Synonyms
(+/-)-4-HeptanolideHeptan-4-olide1,4-Heptanolide2(3H)-Furanone, dihydro-5-propyl-4-Hydroxyheptanoic acid, gamma-lactoneBRN 0109569Dihydro-5-propyl-2(3H)-furanoneEINECS 203-279-9FEMA No. 2539gamma-HeptanolactoneHeptanolide-4,14-Hydroxyheptanoic acid lactone

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 20 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
SCIL (9/2019)USEPASafer Chemical Ingredients List
EuropeEuropean CommissionFl@vis

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records
StatusNameEC NumberLink
RegisteredHeptan-4-olide203-279-9ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed CHEMBL365316
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What regulatory lists include Gamma-Heptalactone?

Gamma-Heptalactone appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), SCIL (9/2019), and 1 more. Source: EPA CPDat.

Is Gamma-Heptalactone used in cosmetics?

Yes, Gamma-Heptalactone is also indexed as a cosmetic ingredient under the name gamma-Heptalactone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Gamma-Heptalactone come from?

Safety data is sourced from EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Gamma-Heptalactone used outside industrial chemicals?

Gamma-Heptalactone also appears in cosmetics, pharmaceutical, cannabis databases.