gamma-Heptalactone

INCI: GAMMA-HEPTALACTONE

CAS Number
105-21-5
Function
Fragrance / flavoring agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS; no 21 CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Marginal positive in one human maximization test (1/25, not statistically significant). Overall weight of evidence from structural analysis and read-across indicates no concern. Not phototoxic.

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Concern Level: Low

Regulatory Flags

fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is gamma-Heptalactone safe in cosmetics?

Marginal positive in one human maximization test (1/25, not statistically significant). Overall weight of evidence from structural analysis and read-across indicates no concern. Not phototoxic. The EU classifies gamma-Heptalactone as "permitted". Safety rating: GOOD.

Is gamma-Heptalactone allowed in the EU?

gamma-Heptalactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does gamma-Heptalactone do in cosmetics?

gamma-Heptalactone functions as: Fragrance / flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 105-21-5.

What is the Margin of Safety for gamma-Heptalactone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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