What is the NOAEL for (2Z)-3,7-dimethylocta-2,6-dienal?
(2Z)-3,7-dimethylocta-2,6-dienal has 28 NOAEL studies in the database. The lowest reported value is 0.2941 % via Dermal in Human. Source: NTP ICE skin sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
(2Z)-3,7-dimethylocta-2,6-dienal
CAS 106-26-3
(2Z)-3,7-dimethylocta-2,6-dienal (CAS 106-26-3) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
28
SOURCE
Chemical inventory jurisdictions
Regulatory lists
4
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
5 fields
Name
(2Z)-3,7-dimethylocta-2,6-dienal
CAS Number
106-26-3
Molecular Formula
C10H16O
InChI Key
WTEVQBCEXWBHNA-YFHOEESVSA-N
Monoisotopic Mass
152.120115
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| air; detected; emissions; Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 28 of 28 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0.3676 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 0.2941 | % | Concentration, one positive response | Dermal | Human | NTP ICE skin sensitization |
| =9 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 8M466BQL1X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 68 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 3240 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 238.2 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 190.6 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP ICE skin sensitization |
| =423.4 | mg/m3 | LOAEC | inhalation | Rat | ECHA |
| =120 | mg/kg bw/day | LOAEL | oral | Mouse | ECHA |
| =210 | mg/kg bw/day | LOAEL | oral | Rat | ECHA |
| =335 | mg/kg bw/day | LOAEL | oral | Rat | ECHA |
| =345 | mg/kg bw/day | LOAEL | oral | Rat | ECHA |
| =745 | mg/kg bw/day | LOAEL | oral | Mouse | ECHA |
| =790 | mg/kg bw/day | LOAEL | oral | Mouse | ECHA |
| =1068 | mg/kg bw/day | LOAEL | oral | Mouse | ECHA |
| =1140 | mg/kg bw/day | LOAEL | oral | Rat | ECHA |
| =8850 | mg/kg bw/day | LOAEL | oral | Mouse | ECHA |
| =211.7 | mg/m3 | NOAEC | inhalation | Rat | ECHA |
| =60 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =534 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| =570 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =4275 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| =2280 | mg/kg bw/day | NOEL | oral | Rat | ECHA |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 28 of 28 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | (Z)-3,7-dimethylocta-2,6-dienal | 203-379-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include (2Z)-3,7-dimethylocta-2,6-dienal?
(2Z)-3,7-dimethylocta-2,6-dienal appears on 4 regulatory/inventory lists including air; detected; emissions; Europe; Vehicle - car interior, detected; Europe; Vehicle - car interior, IFRA Transparency, and 1 more. Source: EPA CPDat.
Is (2Z)-3,7-dimethylocta-2,6-dienal used in cosmetics?
Yes, (2Z)-3,7-dimethylocta-2,6-dienal is also indexed as a cosmetic ingredient under the name NERAL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (2Z)-3,7-dimethylocta-2,6-dienal come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is (2Z)-3,7-dimethylocta-2,6-dienal used outside industrial chemicals?
(2Z)-3,7-dimethylocta-2,6-dienal also appears in cosmetics, cannabis databases.