NERAL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
8 study endpoints found for NERAL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 345 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 745 mg/kg bw/day | oral | mouse | oral | REACH |
| LOAEL | 210 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 60 mg/kg bw/day | oral | mouse | oral | REACH |
| LOAEL | 1140 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 2280 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 8850 mg/kg bw/day | oral | mouse | oral | REACH |
| NOAEL | 534 mg/kg bw/day | oral | mouse | oral | REACH |
Expert Verdict
NERAL is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions.
Regulatory Flags
Frequently Asked Questions
Is NERAL safe in cosmetics?
NERAL is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions. The EU classifies NERAL as "Permitted". Safety rating: GOOD. 8 toxicological study endpoint(s) are available in our database.
Is NERAL allowed in the EU?
NERAL EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NERAL do in cosmetics?
NERAL functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 106-26-3.
What is the NOAEL for NERAL?
The NOAEL (No Observed Adverse Effect Level) for NERAL is 345 mg/kg bw/day based on a oral study via oral route in rat. A total of 8 study endpoints are available. Source: REACH.
Compliance Tools
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