What is the NOAEL for L-Taurine?
L-Taurine has 19 NOAEL studies in the database. The lowest reported value is 1EQV5MLY3D UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
L-Taurine
Also known as: Taurine, Ethanesulfonic acid, 2-amino-, 2-amino-Ethanesulfonic acid, Aminoethanesulfonic acid, EINECS 203-483-8 (+15 more)
CAS 107-35-7
L-Taurine (CAS 107-35-7) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
19
SOURCE
chemical inventory jurisdictions
Regulatory lists
8
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
L-Taurine
CAS Number
107-35-7
DTXSID
DTXSID3021304
Molecular Formula
C2H7NO3S
InChI Key
XOAAWQZATWQOTB-UHFFFAOYSA-N
Monoisotopic Mass
125.014664
Synonyms
TaurineEthanesulfonic acid, 2-amino-2-amino-Ethanesulfonic acidAminoethanesulfonic acidEINECS 203-483-8FEMA No. 3813NCI-C60606TaurinumUNII-1EQV5MLY3D1-Aminoethane-2-sulfonate2-Aminoethanesulfonate2-Aminoethylsulfonate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
15 records
pH regulating agentFragranceNo specific technical functionFlavouring and nutrientProcessing aids not otherwise specified
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 19 of 19 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1EQV5MLY3D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1EQV5MLY3D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1EQV5MLY3D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1EQV5MLY3D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =100 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =300 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 50 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 462 | mg/kg bw/day | NOAEL | oral | guinea pig | COSMOS_DB |
| 565 | mg/kg bw/day | NOAEL | oral | guinea pig | COSMOS_DB |
| 700 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =1000 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 2000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 2500 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| =3000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 5000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =50 | mg/kg bw/day | NOEL | injection | Rat | ToxValDB_ECOTOX |
| =300 | mg/kg bw/day | NOEL | injection | Rat | ToxValDB_ECOTOX |
Showing 19 of 19 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Taurine | 203-483-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
TAURINE
ChEMBL Phase
3
Adverse Events
144
Bioactivity
7
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
2 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw | FDA GRAS: FDA has no questions
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include L-Taurine?
L-Taurine appears on 7 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), active_ingredient; Australia, pharmaceutical, and 4 more. Source: EPA CPDat.
Is L-Taurine used in cosmetics?
Yes, L-Taurine is also indexed as a cosmetic ingredient under the name Taurine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for L-Taurine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is L-Taurine used outside industrial chemicals?
L-Taurine also appears in cosmetics, pharmaceutical, food safety, cannabis databases.