Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Taurine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 462 mg/kg bw/day | oral | guinea pig | Short Term Toxicity | COSMOS_DB |
| NOAEL | 565 mg/kg bw/day | oral | guinea pig | Short Term Toxicity | COSMOS_DB |
| NOAEL | 50 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 5000 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 10 mg/kg bw/day | oral | mouse | Neurotoxicity | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | mouse | Reproductive | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | mouse | Neurotoxicity | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Taurine is a multifunctional antioxidant and osmoprotectant with a well-established safety profile in cosmetics, scavenging ROS and protecting against UV-induced oxidative damage at the cellular level.
Regulatory Flags
Frequently Asked Questions
Is Taurine safe in cosmetics?
Taurine is a multifunctional antioxidant and osmoprotectant with a well-established safety profile in cosmetics, scavenging ROS and protecting against UV-induced oxidative damage at the cellular level. The EU classifies Taurine as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Taurine allowed in the EU?
Taurine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Taurine do in cosmetics?
Taurine functions as: Osmoprotectant stabilizing cell volume under hypertonic or oxidative stress. Scavenges hypochlorous acid and other reactive oxygen species (ROS). Protects against UV-induced damage and supports keratinocyte viability. Functions as a free intracellular antioxidant (not incorporated into proteins).. It is classified as a Antioxidant in our database. CAS number: 107-35-7.
What is the Margin of Safety for Taurine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Taurine?
The NOAEL (No Observed Adverse Effect Level) for Taurine is 462 mg/kg bw/day based on a Short Term Toxicity study via oral route in guinea pig. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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