Is Taurine safe in cosmetics?
Taurine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 7 toxicological study endpoint(s) are available in our database.
Taurine
Also known as: Ethanesulfonic acid, 2-amino-, 2-amino-Ethanesulfonic acid, Aminoethanesulfonic acid, EINECS 203-483-8, FEMA No. 3813 (+14 more)
INCI: TAURINE
Taurine (CAS 107-35-7) is a cosmetic antioxidant functioning as Osmoprotectant stabilizing cell volume under hypertonic or oxidative stress. Reported NOAEL 462 mg/kg bw/day in guinea pig (COSMOS_DB); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 107-35-7 →
Auto-generated CPSR Part A draft with source citations
Function
Osmoprotectant stabilizing cell volume under hypertonic or oxidative stress. Scavenges hypochlorous acid and other reactive oxygen species (ROS). Protects against UV-induced damage and supports keratinocyte viability. Functions as a free intracellular antioxidant (not incorporated into proteins).
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA restrictions; used as a cosmetic active.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Taurine.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for Taurine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 462 mg/kg bw/day | oral | guinea pig | Short Term Toxicity | COSMOS_DB |
| NOAEL | 565 mg/kg bw/day | oral | guinea pig | Short Term Toxicity | COSMOS_DB |
| NOAEL | 700 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | mouse | Reproductive | COSMOS_DB |
| NOAEL | 5000 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | =3000 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
EPA ToxValDB — Toxicity Values
10 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LD50 | >7000 mg/kg | Mouse | oral | - | ECHA IUCLID |
| LD50 | >5000 mg/kg | Rat | oral | - | ECHA IUCLID |
| LD50 | >2000 mg/kg | Rat | oral | - | ECHA IUCLID |
| LEL | =100 mg/kg-day | Rat | oral | subchronic | ECHA IUCLID |
| LOAEL | =50 mg/kg-day | Rat | oral | subchronic | ECHA IUCLID |
| LOAEL | =300 mg/kg-day | Rat | oral | subchronic | ECHA IUCLID |
| NOAEL | =3000 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| NOAEL | =3000 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| NOAEL | =1000 mg/kg-day | Rat | oral | subchronic | EFSA |
| NOEL | =50 mg/kg-day | Rat | injection | subchronic | ECOTOX |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
7 property records from structured ingredient metadata.
acne
{"cas_number": "107-35-7", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_a…
amino_acid
{"cas_number": "107-35-7", "ingredient_class": "amino_acid", "source_origin": "synthetic", "molecular_weight_range_Da": "125", "amino_acid_composition_key": "sulfonic_acid", "charge_at_pH_5_5": "zwitterionic", "water_solubility": "soluble", "oil_solubility": "insoluble", "film_forming_ability": "poor", "moisture_binding_capacity": "good", "NMF_component": "yes", "skin_penetration_depth": "epidermi…
anti_aging
{"anti_aging_claim": "antioxidant-protection, anti-inflammatory", "mechanism_of_action": "Building block for proteins, NMF component", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "6-12", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Int…
anti_pollution
{"cas_number": "107-35-7", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_inhibitio…
antioxidant
{"cas_number": "107-35-7", "antioxidant_class": "thiol", "chemical_subclass": "amino sulfonic acid", "molecular_weight_daltons": "125.15", "orac_value_umol_te_per_g": "850", "dpph_radical_scavenging_ic50_ug_per_ml": "50-85", "abts_trolox_equivalent": "not available", "singlet_oxygen_quenching": "not available", "superoxide_dismutase_mimetic": "not available", "hydroxyl_radical_scavenging": "not av…
humectant
{"cas_number": "107-35-7", "ingredient_class": "humectant/amino_acid/osmolyte", "molecular_weight_Da": "125.15", "chemical_type": "amino_acid", "water_binding_mechanism": "hydrogen_bonding/osmotic", "water_holding_capacity_g_per_g": "0.3-0.5", "hygroscopicity_at_50_RH": "moderate", "hygroscopicity_at_80_RH": "good", "NMF_component": "no", "NMF_percentage_natural": "0", "TEWL_reduction_pct": "12-22…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
No specific technical function
Processing aids not otherwise specified
pH regulating agent
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Taurine.
Regulatory Flags
epa_safer_alternative
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Taurine by CAS number or substance name.
Studies
7
Lowest NOAEL
462 mg/kg bw/day
Highest NOAEL
5000 mg/kg bw/day
COSMOS_DB
ToxValDB_ECHA_IUCLID
Known Synonyms
Ethanesulfonic acid, 2-amino-
2-amino-Ethanesulfonic acid
Aminoethanesulfonic acid
EINECS 203-483-8
FEMA No. 3813
NCI-C60606
Taurinum
UNII-1EQV5MLY3D
1-Aminoethane-2-sulfonate
2-Aminoethanesulfonate
2-Aminoethylsulfonate
2-aminoethane-1-sulfonic acid
2-aminoethyl sulfonate
Aminoethylsulfonate
b-Aminoethylsulfonate
b-Aminoethylsulfonic acid
beta-Aminoethylsulfonate
beta-aminoethylsulfonic acid
2-ammonioethanesulfonate
Chemical Function
pH regulating agent
Fragrance
No specific technical function
Flavouring and nutrient
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
active_ingredient; Australia
pharmaceutical
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
SCIL (9/2019)
Canada; pharmaceutical
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
TAURINE
ChEMBL ID
CHEMBL239243
Max Phase
3
Adverse Event Associations
144
SOURCE
EFSA / FDA GRAS
food_additives + fda_gras_enriched
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Taurine
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
FDA GRAS
FDA has no questions
GRN
586
Food Category
preservative
For use as an ingredient in enhanced water beverages at a concentration of 45 parts per million (0.0045%).
View full food safety profile →Frequently Asked Questions
Is Taurine allowed in the EU?
Taurine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Taurine do in cosmetics?
Taurine functions as: Osmoprotectant stabilizing cell volume under hypertonic or oxidative stress. Scavenges hypochlorous acid and other reactive oxygen species (ROS). Protects against UV-induced damage and supports keratinocyte viability. Functions as a free intracellular antioxidant (not incorporated into proteins).. It is classified as a Antioxidant in our database. CAS number: 107-35-7.
What is the NOAEL for Taurine?
The NOAEL (No Observed Adverse Effect Level) for Taurine is 462 mg/kg bw/day based on a Short Term Toxicity study via oral route in guinea pig. A total of 7 study endpoints are available. Source: COSMOS_DB.
Is Taurine used outside cosmetics?
Taurine also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Taurine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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