Also known as: Ethanol, 2-[(3-aminopyrazolo[1,5-a]pyridin-2-yl)oxy]-, hydrochloride (1:1), 2-((3-Aminopyrazolo[1,5-a]pyridin-2-yl)oxy)ethanol hydrochloride (1:1), 2-(2-Hydroxyethoxy)-3-aminopyrazolo[1,5-a]pyridine hydrochloride, 2-[(3-Aminopyrazolo[1,5-a]pyridin-2-yl)oxy]ethan-1-ol hydrochloride, EC No.: 695-745-7 (+3 more)
CAS 1079221-49-0
2-[(3-Aminopyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol hydrochloride (1:1) (CAS 1079221-49-0) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, SCCS, ECHA REACH.
View cosmetic safety profile for Hydroxyethoxy Aminopyrazolopyridine HCl →
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care; restricted | European Commission | CosIng |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 100 | mg/kg bw/day | - | - | rat | Regulatory source |
| =1.67 | mg/kg bw/d | NOAEL | oral | human | SCCS Opinion |
| =3.33 | mg/kg bw/d | NOAEL | oral | human | SCCS Opinion |
| =10 | mg/kg bw/day | NOAEL | - | - | SCCS Opinion |
| =10 | mg/kg/day | NOAEL | - | - | SCCS Opinion |
| =30 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =30 | mg/kg bw/day | NOAEL | oral | rat | SCCS Opinion |
| =100 | mg/kg bw/day | NOAEL | - | rat | SCCS Opinion |
| 10 | mg/kg bw/day | dermal absorption | dermal | human | Regulatory source |
| =1.67 | mg/kg bw/d | developmental toxicity | oral | human | Regulatory source |
| =3.33 | mg/kg bw/d | developmental toxicity | oral | human | Regulatory source |
| 10 | mg/kg/day | developmental toxicity | - | - | Regulatory source |
| 10 | mg/kg bw/day | developmental toxicity | oral | rat | Regulatory source |
| 30 | mg/kg bw/day | developmental toxicity | oral | rat | Regulatory source |
| 10 | mg/kg bw/day | genotoxicity | - | - | Regulatory source |
Showing 15 of 15 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-[(3-aminopyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol hydrochloride | 695-745-7 | ECHA overview → |
EU Scientific Committee opinions tied to the matched substance.
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCS/1530/14 | 18 June 2014 | safe | 2.0% | strong sensitiser |
Same-CAS cosmetic ingredient record for cross-vertical context.
2-[(3-Aminopyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol hydrochloride (1:1) has 15 NOAEL studies in the database. The lowest reported value is 1.67 mg/kg bw/d via oral in human. Source: SCCS Opinion.
2-[(3-Aminopyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol hydrochloride (1:1) appears on 1 regulatory/inventory list including Europe; Personal care; restricted. Source: EPA CPDat.
Yes, 2-[(3-Aminopyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol hydrochloride (1:1) is also indexed as a cosmetic ingredient under the name Hydroxyethoxy Aminopyrazolopyridine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
2-[(3-Aminopyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol hydrochloride (1:1) also appears in cosmetics databases.