What regulatory lists include 4-Pentanolide?
4-Pentanolide appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe, and 1 more. Source: EPA CPDat.
REACH Registered
Cosmetic Ingredient
4-Pentanolide
Also known as: gamma-Valerolactone, 5-17-09-00024, BRN 0080420, EINECS 203-569-5, FEMA No. 3103 (+15 more)
CAS 108-29-2
4-Pentanolide (CAS 108-29-2) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
0
SOURCE
Chemical inventory jurisdictions
Regulatory lists
4
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
4-Pentanolide
CAS Number
108-29-2
Molecular Formula
C5H8O2
InChI Key
GAEKPEKOJKCEMS-UHFFFAOYSA-N
Monoisotopic Mass
100.052429
Synonyms
gamma-Valerolactone5-17-09-00024BRN 0080420EINECS 203-569-5FEMA No. 31032(3H)-Furanone, dihydr-5-methyl-gamma-Methyl-gamma-butyrolactonePentanoic acid, 4-hydroxy-, gamma-lactonePentanolide-1,4Valeric acid, 4-hydroxy-, gamma-lactonegamma-Valeryllactonegamma-Valerolakton
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
9 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
| consumer_product | P&G | Proctor & Gamble |
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | γ-valerolactone | 203-569-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CHEMBL195593
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is 4-Pentanolide used in cosmetics?
Yes, 4-Pentanolide is also indexed as a cosmetic ingredient under the name gamma-Valerolactone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-Pentanolide come from?
Safety data is sourced from EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 4-Pentanolide used outside industrial chemicals?
4-Pentanolide also appears in cosmetics, pharmaceutical, food safety, cannabis databases.