What is the NOAEL for Ethyl isovalerate?
Ethyl isovalerate has 8 NOAEL studies in the database. The lowest reported value is 9ZZ5597636 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ethyl isovalerate
Also known as: BRN 1744677, Butyric acid, 3-methyl-, ethyl ester, EINECS 203-602-3, FEMA No. 2463, UNII-9ZZ5597636 (+6 more)
CAS 108-64-5
Ethyl isovalerate (CAS 108-64-5) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Ethyl isovalerate
CAS Number
108-64-5
DTXSID
DTXSID3047057
Molecular Formula
C7H14O2
InChI Key
PPXUHEORWJQRHJ-UHFFFAOYSA-N
Monoisotopic Mass
130.09938
Synonyms
BRN 1744677Butyric acid, 3-methyl-, ethyl esterEINECS 203-602-3FEMA No. 2463UNII-9ZZ5597636Butyric acid, 3-methyl-, ethyl ester (6CI,7CI,8CI)Ethyl beta-methylbutyrateEthyl iso-pentanoateEthyl isovalerianateEthylisovalerateFEMA 2463
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
20 records
FragranceNo specific technical functionFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| consumer_product | P&G | Proctor & Gamble |
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 9ZZ5597636 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9ZZ5597636 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9ZZ5597636 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9ZZ5597636 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 12.5 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ethyl isovalerate | 203-602-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3183097
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Ethyl isovalerate?
Ethyl isovalerate appears on 6 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 3 more. Source: EPA CPDat.
Is Ethyl isovalerate used in cosmetics?
Yes, Ethyl isovalerate is also indexed as a cosmetic ingredient under the name Ethyl Isovalerate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ethyl isovalerate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Ethyl isovalerate used outside industrial chemicals?
Ethyl isovalerate also appears in cosmetics, pharmaceutical, cannabis databases.