What is the NOAEL for Oxacycloheptadecan-2-one?
Oxacycloheptadecan-2-one has 10 NOAEL studies in the database. The lowest reported value is 64E2HO00C7 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Oxacycloheptadecan-2-one
Also known as: 16-Hexadecanolide, 5-17-09-00108, BRN 0148631, Cyclohexadecanolide, Dihydroambrettolide (+11 more)
CAS 109-29-5
Oxacycloheptadecan-2-one (CAS 109-29-5) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
Oxacycloheptadecan-2-one
CAS Number
109-29-5
DTXSID
DTXSID4047622
Molecular Formula
C16H30O2
InChI Key
LOKPJYNMYCVCRM-UHFFFAOYSA-N
Monoisotopic Mass
254.22458
Synonyms
16-Hexadecanolide5-17-09-00108BRN 0148631CyclohexadecanolideDihydroambrettolideEINECS 203-662-01,16-HexadecalactoneHexadecanoic acid, 16-hydroxy-, omicron-lactone1,16-Hexadecanolactone16-HexadecanolactoneHexadecanolide1,16-Hexadecanolide
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
DeodorizerFragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 64E2HO00C7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 64E2HO00C7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 64E2HO00C7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 64E2HO00C7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 465 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 4 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Oxacycloheptadecan-2-one | 203-662-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3189021
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Oxacycloheptadecan-2-one?
Oxacycloheptadecan-2-one appears on 4 regulatory/inventory lists including Europe, IFRA Transparency, consumer_product, and 1 more. Source: EPA CPDat.
Is Oxacycloheptadecan-2-one used in cosmetics?
Yes, Oxacycloheptadecan-2-one is also indexed as a cosmetic ingredient under the name Hexadecanolactone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Oxacycloheptadecan-2-one come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Oxacycloheptadecan-2-one used outside industrial chemicals?
Oxacycloheptadecan-2-one also appears in cosmetics, pharmaceutical, cannabis databases.