What is the NOAEL for 2-Hydroxyethyl octadecanoate?
2-Hydroxyethyl octadecanoate has 4 NOAEL studies in the database. The lowest reported value is 0324G66D0E UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Hydroxyethyl octadecanoate
Also known as: Octadecanoic acid, 2-hydroxyethyl ester, Ethylene glycol, monostearate, 2-Hydroxyethyl stearate, BRN 1794033, Clindrol SEG (+4 more)
CAS 111-60-4
2-Hydroxyethyl octadecanoate (CAS 111-60-4) is a chemical substance. Key regulatory status: 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
2-Hydroxyethyl octadecanoate
CAS Number
111-60-4
DTXSID
DTXSID5026881
Molecular Formula
C20H40O3
InChI Key
RFVNOJDQRGSOEL-UHFFFAOYSA-N
Monoisotopic Mass
328.297745
Synonyms
Octadecanoic acid, 2-hydroxyethyl esterEthylene glycol, monostearate2-Hydroxyethyl stearateBRN 1794033Clindrol SEGEINECS 203-886-9Lipo EGMSStearic acid, monoester with ethylene glycolUNII-0324G66D0E
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
EmulsifierSurfactant (surface active agent)Softener and conditionerOpaciferStabilizing agentThickening agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - body hygiene - body wash | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - hair styling and care - shampoo | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - specialized bath products - bubble bath | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0324G66D0E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0324G66D0E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0324G66D0E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0324G66D0E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emulsifier
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL2355383
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include 2-Hydroxyethyl octadecanoate?
2-Hydroxyethyl octadecanoate appears on 6 regulatory/inventory lists including SCIL (9/2019), children; Europe; Personal care, children; Europe; Personal care - body hygiene - body wash, and 3 more. Source: EPA CPDat.
Is 2-Hydroxyethyl octadecanoate used in cosmetics?
Yes, 2-Hydroxyethyl octadecanoate is also indexed as a cosmetic ingredient under the name Glycol Stearate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Hydroxyethyl octadecanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Hydroxyethyl octadecanoate used outside industrial chemicals?
2-Hydroxyethyl octadecanoate also appears in cosmetics, pharmaceutical databases.