Is Glycol Stearate safe in cosmetics?
Glycol Stearate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Glycol Stearate
Also known as: Octadecanoic acid, 2-hydroxyethyl ester, Ethylene glycol, monostearate, 2-Hydroxyethyl stearate, BRN 1794033, Clindrol SEG (+4 more)
INCI: GLYCOL STEARATE
Glycol Stearate (CAS 111-60-4) is a cosmetic cosmetic ingredient functioning as Emollient, emulsifying agent, opacifier, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 111-60-4 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient, emulsifying agent, opacifier, skin conditioning
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2-hydroxyethyl octadecanoate
InChIKey
RFVNOJDQRGSOEL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — CIR assessed safe; no 21 CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glycol Stearate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "2.9", "co_emulsifier_pairs": "sorbitan_oleate,glyceryl_stearate", "optimal_oil_phase_pct": "60-85", "optimal_water_phase_pct": "15-40", "droplet_size_range_um": "8-70", "creaming_resistance": "poor", "coalescence_resistance": "excellent", "ostwald_ripening_resistance": "excellent", "freeze_thaw_stability": "moderate", "rheology_mod…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Evidence for Carcinogenicity
A4; Not classifiable as a human carcinogen. /Stearates; does not include stearates of toxic metals/
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Opacifer
Softener and conditioner
Stabilizing agent
Surfactant (surface active agent)
Thickening agent
Viscosity modifier
Regulatory List Membership (2)
EU Restricted for Children (Cosmetics)
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for Glycol Stearate.
Regulatory Flags
eu_children_restricted
epa_safer_alternative
Known Synonyms
Octadecanoic acid, 2-hydroxyethyl ester
Ethylene glycol, monostearate
2-Hydroxyethyl stearate
BRN 1794033
Clindrol SEG
EINECS 203-886-9
Lipo EGMS
Stearic acid, monoester with ethylene glycol
UNII-0324G66D0E
Chemical Function
Emulsifier
Surfactant (surface active agent)
Softener and conditioner
Opacifer
Stabilizing agent
Regulatory Lists
SCIL (9/2019)
children; Europe; Personal care
children; Europe; Personal care - body hygiene - body wash
children; Europe; Personal care - hair styling and care - shampoo
children; Europe; Personal care - specialized bath products - bubble bath
children; Europe; Personal care
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL2355383
Frequently Asked Questions
Is Glycol Stearate allowed in the EU?
Glycol Stearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glycol Stearate do in cosmetics?
Glycol Stearate functions as: Emollient, emulsifying agent, opacifier, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 111-60-4.
Is Glycol Stearate used outside cosmetics?
Glycol Stearate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Glycol Stearate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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