What is the NOAEL for Ammonium carbamate?
Ammonium carbamate has 8 NOAEL studies in the database. The lowest reported value is 49.8 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ammonium carbamate
Also known as: Carbamic acid, monoammonium salt, Ammonium aminoformate, "Anhydride" of ammonium carbonate, EINECS 214-185-2, UNII-I2W9615SWP (+1 more)
CAS 1111-78-0
Ammonium carbamate (CAS 1111-78-0) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Ammonium carbamate is classified GHS Danger (H302, H315, H318) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Ammonium carbamate
CAS Number
1111-78-0
DTXSID
DTXSID9027360
Molecular Formula
CH3NO2.H3N
InChI Key
BVCZEBOGSOYJJT-UHFFFAOYSA-N
Monoisotopic Mass
78.042927
Synonyms
Carbamic acid, monoammonium saltAmmonium aminoformate"Anhydride" of ammonium carbonateEINECS 214-185-2UNII-I2W9615SWPCarbamic acid, ammonium salt (1:1)
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
pH regulating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =49.8 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| I2W9615SWP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I2W9615SWP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I2W9615SWP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I2W9615SWP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >681 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| <1470 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ammonium carbamate | 214-185-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3560381
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Ammonium carbamate?
Ammonium carbamate appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, active_ingredient; Pesticides. Source: EPA CPDat.
Is Ammonium carbamate used in cosmetics?
Yes, Ammonium carbamate is also indexed as a cosmetic ingredient under the name Ammonium Carbamate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ammonium carbamate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Ammonium carbamate have different safety status in cosmetics vs industrial chemicals?
Ammonium carbamate is classified GHS Danger (H302, H315, H318) in the chemicals database but is allowed in EU cosmetics.
Is Ammonium carbamate used outside industrial chemicals?
Ammonium carbamate also appears in cosmetics, pharmaceutical databases.