Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Ammonium Carbamate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | ca.2214.5 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | ca.1695.7 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 474 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 684 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Component of commercial Ammonium Carbonate mixture; releases ammonia upon decomposition; ensure adequate pH buffering in formulation
Frequently Asked Questions
Is Ammonium Carbamate safe in cosmetics?
Component of commercial Ammonium Carbonate mixture; releases ammonia upon decomposition; ensure adequate pH buffering in formulation The EU classifies Ammonium Carbamate as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.
Is Ammonium Carbamate allowed in the EU?
Ammonium Carbamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Carbamate do in cosmetics?
Ammonium Carbamate functions as: Buffering. It is classified as a cosmetic ingredient in our database. CAS number: 1111-78-0.
What is the Margin of Safety for Ammonium Carbamate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ammonium Carbamate?
The NOAEL (No Observed Adverse Effect Level) for Ammonium Carbamate is ca.2214.5 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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