Also known as: Neopental glycol monohydroxypivalate, Propanoic acid, 3-hydroxy-2,2-dimethyl-, 3-hydroxy-2,2-dimethylpropyl ester, EINECS 214-222-2, Esterdiol 204, Hydracrylic acid, 2,2-dimethyl-, 3-hydroxy-2,2-dimethylpropyl ester (+6 more)
CAS 1115-20-4
3-Hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropanoate (CAS 1115-20-4) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for 3-Hydroxy-2,2-Dimethylpropyl Hydroxypivalate →
3-Hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropanoate is classified GHS Danger (H318, H319) in the chemicals database but is allowed in EU cosmetics.
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =10.45 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| CG0A37GAHJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CG0A37GAHJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CG0A37GAHJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CG0A37GAHJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 7 of 7 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropionate | 214-222-2 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
3-Hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropanoate has 7 NOAEL studies in the database. The lowest reported value is 10.45 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
Yes, 3-Hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropanoate is also indexed as a cosmetic ingredient under the name 3-Hydroxy-2,2-Dimethylpropyl Hydroxypivalate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
3-Hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropanoate is classified GHS Danger (H318, H319) in the chemicals database but is allowed in EU cosmetics.
3-Hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropanoate also appears in cosmetics, pharmaceutical databases.