What is the NOAEL for 10-Undecenoic acid?
10-Undecenoic acid has 58 NOAEL studies in the database. The lowest reported value is -0.1 % via Dermal. Source: NTP ICE skin sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
10-Undecenoic acid
Also known as: Undecylenic acid, 4-02-00-01612, BRN 1762631, Caswell No. 901, Desenex (+15 more)
CAS 112-38-9
10-Undecenoic acid (CAS 112-38-9) is a chemical substance. Key regulatory status: REACH registered, 31 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
58
SOURCE
Chemical inventory jurisdictions
Regulatory lists
31
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
10-Undecenoic acid
CAS Number
112-38-9
Molecular Formula
C11H20O2
InChI Key
FRPZMMHWLSIFAZ-UHFFFAOYSA-N
Monoisotopic Mass
184.14633
Synonyms
Undecylenic acid4-02-00-01612BRN 1762631Caswell No. 901DesenexEINECS 203-965-8EPA Pesticide Chemical Code 085501FEMA No. 3247Hendecenoic acid, omega-Undecenoic acid, omega-Undecyl-10-enic acid9-Undecylenic acid
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
20 records
Surfactant (surface active agent)PreservativeEmulsifierCleaning agentFragranceBiocideFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
31 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | European Commission | CosIng |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| Europe | European Commission | Fl@vis |
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| Europe; Personal care - body hygiene - hand soap | Danish Environmental Protection Agency | Danish EPA |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 58 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =5.92 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 11.4 | % | Depletion Cys | Dermal | - | NTP ICE skin sensitization |
| -0.1 | % | Depletion Lys | Dermal | - | NTP ICE skin sensitization |
| 5.75 | % | Depletion Lys + Cys | Dermal | - | NTP ICE skin sensitization |
| 57 | uM | EC1.5 | Dermal | - | NTP ICE skin sensitization |
| <172.4 | uM | EC1.5 | Dermal | - | NTP ICE skin sensitization |
| 19.4 | % | EC3 | Dermal | Mouse | NTP ICE skin sensitization |
| 25 | % | EC3 | Dermal | Mouse | NTP ICE skin sensitization |
| 6.2 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 6.4 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 7.1 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 15.5 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 18.5 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 22.1 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 28.5 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 33.5 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 34.2 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| K3D86KJ24N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >428.9 | uM | IC50 | Dermal | - | NTP ICE skin sensitization |
| >2000 | uM | IC50 | Dermal | - | NTP ICE skin sensitization |
| 8.048 | ratio | Imax | Dermal | - | NTP ICE skin sensitization |
| 23.3 | ratio | Imax | Dermal | - | NTP ICE skin sensitization |
| 0 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =2500 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| 0 | unitless | Model Score | - | - | NTP ICE endocrine |
| =150 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =450 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 3.5 | % | Positive reaction | Dermal | Human | NTP ICE skin irritation |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
| 5.3 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 5.6 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 7 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 8.3 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 8.4 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 10 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 10.2 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 10.42 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 12.1 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 12.3 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 12.5 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 12.6 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 17.5 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 23.8 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 31.05 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 33.2 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 13 | % | Viability (18 hours) | Dermal | - | NTP ICE skin irritation |
| 60 | % | Viability (240 minutes) | Dermal | - | NTP ICE skin irritation |
| 101.6 | % | Viability (240 minutes) | Dermal | - | NTP ICE skin irritation |
Showing 50 of 58 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Undec-10-enoic acid | 203-965-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
UNDECYLENIC ACID
ChEMBL Phase
-1
Adverse Events
84
Bioactivity
5
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 10-Undecenoic acid?
10-Undecenoic acid appears on 11 regulatory/inventory lists including Europe; Personal care, active_ingredient; Europe; Pesticides, Europe, and 8 more. Source: EPA CPDat.
Is 10-Undecenoic acid used in cosmetics?
Yes, 10-Undecenoic acid is also indexed as a cosmetic ingredient under the name Undecylenic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 10-Undecenoic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 10-Undecenoic acid used outside industrial chemicals?
10-Undecenoic acid also appears in cosmetics, pharmaceutical, food safety, cannabis databases.