What is the NOAEL for 1-Tetradecanol?
1-Tetradecanol has 49 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP ICE skin sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1-Tetradecanol
Also known as: lMyristyl alcohol, C14 alcohol, 4-01-00-01864, Alcohol(C14), BRN 1742652 (+13 more)
CAS 112-72-1
1-Tetradecanol (CAS 112-72-1) is a chemical substance. Key regulatory status: REACH registered, 22 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
49
SOURCE
Chemical inventory jurisdictions
Regulatory lists
22
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
1-Tetradecanol
CAS Number
112-72-1
DTXSID
DTXSID9026926
Molecular Formula
C14H30O
InChI Key
HLZKNKRTKFSKGZ-UHFFFAOYSA-N
Monoisotopic Mass
214.229666
Synonyms
lMyristyl alcoholC14 alcohol4-01-00-01864Alcohol(C14)BRN 1742652EINECS 204-000-3Fatty alcohol(C14)UNII-V42034O9PUAdol 18Alfol 14Conol 1495Kalcohl 40
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
38 records
OpaciferSoftener and conditionerViscosity modifierEmulsifierFoamantStabilizing agentThickening agentFragranceSurfactant (surface active agent)Flavouring and nutrientPlasticizerLubricating agentSolventProcessing aids not otherwise specified
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
22 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 49 of 49 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 25.7456339608277 | uM | AC50 | - | - | NTP ICE endocrine |
| 6.96973943208125 | uM | ACC | - | - | NTP ICE endocrine |
| 7.5 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 6 | % | Concentration, one positive response | Dermal | Human | NTP ICE skin sensitization |
| 4 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP ICE eye irritation |
| 4 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP ICE eye irritation |
| 4 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP ICE eye irritation |
| 4 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP ICE eye irritation |
| 3 | unitless | EPA Classification | Ocular | Rabbit | NTP ICE eye irritation |
| 3 | unitless | EPA Classification | Ocular | Rabbit | NTP ICE eye irritation |
| 3 | unitless | EPA Classification | Ocular | Rabbit | NTP ICE eye irritation |
| 3 | unitless | EPA Classification | Ocular | Rabbit | NTP ICE eye irritation |
| V42034O9PU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V42034O9PU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V42034O9PU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V42034O9PU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2 | unitless | GHS Classification | Ocular | Rabbit | NTP ICE eye irritation |
| 2 | unitless | GHS Classification | Ocular | Rabbit | NTP ICE eye irritation |
| 2 | unitless | GHS Classification | Ocular | Rabbit | NTP ICE eye irritation |
| 2 | unitless | GHS Classification | Ocular | Rabbit | NTP ICE eye irritation |
| - | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 8 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 7776 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 4860 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 3888 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP ICE skin sensitization |
| 0.03 | %/sec | Intensity | Ocular | - | NTP ICE eye irritation |
| 0.03 | %/sec | Intensity | Ocular | - | NTP ICE eye irritation |
| 0.03 | %/sec | Intensity | Ocular | - | NTP ICE eye irritation |
| 0.03 | %/sec | Intensity | Ocular | - | NTP ICE eye irritation |
| >0.7 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| >1.5 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| >2.05 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| >21 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| >71 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| >1500 | mg/m3 | LEL | inhalation | Rat | ECHA |
| >180 | s | Lag time | Ocular | - | NTP ICE eye irritation |
| >180 | s | Lag time | Ocular | - | NTP ICE eye irritation |
| >180 | s | Lag time | Ocular | - | NTP ICE eye irritation |
| >180 | s | Lag time | Ocular | - | NTP ICE eye irritation |
| - | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.0143 | unitless | Model Score | - | - | NTP ICE endocrine |
| - | % | Plateau level | Ocular | - | NTP ICE eye irritation |
| - | % | Plateau level | Ocular | - | NTP ICE eye irritation |
| - | % | Plateau level | Ocular | - | NTP ICE eye irritation |
| - | % | Plateau level | Ocular | - | NTP ICE eye irritation |
| - | % | Positive reaction | Dermal | Human | NTP ICE skin irritation |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 49 of 49 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Tetradecanol | 204-000-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Thickener/Rheology
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
MYRISTYL ALCOHOL
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
2
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1-Tetradecanol?
1-Tetradecanol appears on 7 regulatory/inventory lists including IFRA Transparency, SCIL (9/2019), active_ingredient; Pesticides, and 4 more. Source: EPA CPDat.
Is 1-Tetradecanol used in cosmetics?
Yes, 1-Tetradecanol is also indexed as a cosmetic ingredient under the name Myristyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-Tetradecanol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 1-Tetradecanol used outside industrial chemicals?
1-Tetradecanol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.