Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Myristyl Alcohol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | 3548 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1127 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >4257 other | oral | rat | oral | REACH |
| NOAEL | >2000 mg/kg bw/day | oral | dog | oral | REACH |
| NOAEL | 130 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 184 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 4150 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
CIR determined safe as used; practically nontoxic via all routes with oral LD50 >8 g/kg; non-sensitizer at cosmetic levels.
Regulatory Flags
Frequently Asked Questions
Is Myristyl Alcohol safe in cosmetics?
CIR determined safe as used; practically nontoxic via all routes with oral LD50 >8 g/kg; non-sensitizer at cosmetic levels. The EU classifies Myristyl Alcohol as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Myristyl Alcohol allowed in the EU?
Myristyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Myristyl Alcohol do in cosmetics?
Myristyl Alcohol functions as: Emollient, emulsion stabilizer, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 112-72-1.
What is the Margin of Safety for Myristyl Alcohol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Myristyl Alcohol?
The NOAEL (No Observed Adverse Effect Level) for Myristyl Alcohol is 1000 mg/kg bw/day based on a dermal study via dermal route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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