Is Myristyl Alcohol safe in cosmetics?
Myristyl Alcohol has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
EXCELLENT
Cosmetic Ingredient
Myristyl Alcohol
Also known as: lMyristyl alcohol, C14 alcohol, 4-01-00-01864, Alcohol(C14), BRN 1742652 (+13 more)
INCI: MYRISTYL ALCOHOL
Myristyl Alcohol (CAS 112-72-1) is a cosmetic cosmetic ingredient functioning as Emollient, emulsion stabilizer, viscosity controlling. NOAEL 128 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
Function
Emollient, emulsion stabilizer, viscosity controlling
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
tetradecan-1-ol
InChIKey
HLZKNKRTKFSKGZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA food additive under 21 CFR 172.864. CTFA purity specs: >=99% total alcohols, >=96% straight-chain.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Myristyl Alcohol.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Myristyl Alcohol across SCCS product categories, with measured dermal absorption where available.
Sensitization AOP Dashboard
Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.
NESIL
7776 µg/cm²
GHS: 1B
Human: positive
Source: HPPT: [264] Kligman AM (1974): Report to RIFM, 5 June and 20 August, unpublished.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 7776 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100,000 - 1,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Flavouring and nutrient
Foamant
Fragrance
Lubricating agent
Opacifer
Plasticizer
Processing aids not otherwise specified
Softener and conditioner
Solvent
Regulatory List Membership (4)
EU Regulated in Personal Care
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Editorial summary
Preliminary editorial summary for Myristyl Alcohol — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
epa_safer_alternative
ifra_fragrance
fda_food_additive
Known Synonyms
lMyristyl alcohol
C14 alcohol
4-01-00-01864
Alcohol(C14)
BRN 1742652
EINECS 204-000-3
Fatty alcohol(C14)
UNII-V42034O9PU
Adol 18
Alfol 14
Conol 1495
Kalcohl 40
Lanette 14
Lorol C 14
Myristic alcohol
Tetradecanol (7CI)
n-Tetradecanol-1
tetradecanol
Chemical Function
Opacifer
Softener and conditioner
Viscosity modifier
Emulsifier
Foamant
Regulatory Lists
IFRA Transparency
SCIL (9/2019)
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Europe; Personal care
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
MYRISTYL ALCOHOL
ChEMBL ID
CHEMBL24022
Max Phase
-1
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
MYRISTYL ALCOHOL
Food Category
food_additive
Frequently Asked Questions
Is Myristyl Alcohol allowed in the EU?
Myristyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Myristyl Alcohol do in cosmetics?
Myristyl Alcohol functions as: Emollient, emulsion stabilizer, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 112-72-1.
Is Myristyl Alcohol used outside cosmetics?
Myristyl Alcohol also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Myristyl Alcohol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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