What is the NOAEL for Bromophenol blue?
Bromophenol blue has 10 NOAEL studies in the database. The lowest reported value is 0 uL/min/10^6 cells in Human. Source: NTP ICE adme parameters.
NOAEL Data
Cosmetic Ingredient
Bromophenol blue
Also known as: 5-19-03-00458, BRN 0061698, EINECS 204-086-2, 3',3'',5',5''-Tetrabromophenolsulfonephthalein, 3,3',5,5'-Tetrabromophenolsulfonphthalein (+3 more)
CAS 115-39-9
Bromophenol blue (CAS 115-39-9) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
NOAEL studies
NOAEL studies
10
SOURCE
Chemical inventory jurisdictions
Regulatory lists
1
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Bromophenol blue
CAS Number
115-39-9
Molecular Formula
C19H10Br4O5S
InChI Key
UDSAIICHUKSCKT-UHFFFAOYSA-N
Monoisotopic Mass
665.698245
Synonyms
5-19-03-00458BRN 0061698EINECS 204-086-23',3'',5',5''-Tetrabromophenolsulfonephthalein3,3',5,5'-TetrabromophenolsulfonphthaleinTetrabromphenol BlueUNII-0R2969YC90bromophenol blue, sultone form
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
BiocideAntioxidant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 4.743 | uM | AC50 | - | - | NTP ICE endocrine |
| 20.83 | uM | AC50 | - | - | NTP ICE endocrine |
| 1.325 | uM | ACC | - | - | NTP ICE endocrine |
| 26.17 | uM | ACC | - | - | NTP ICE endocrine |
| 0 | uL/min/10^6 cells | Clint | - | Human | NTP ICE adme parameters |
| 0R2969YC90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0 | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.0128 | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.0461 | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.232 | unitless | Model Score | - | - | NTP ICE endocrine |
Showing 10 of 10 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
BROMOPHENOL BLUE
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Bromophenol blue?
Bromophenol blue appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Bromophenol blue used in cosmetics?
Yes, Bromophenol blue is also indexed as a cosmetic ingredient under the name Bromphenol Blue. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Bromophenol blue come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Bromophenol blue used outside industrial chemicals?
Bromophenol blue also appears in cosmetics, pharmaceutical databases.