Is Bromphenol Blue safe in cosmetics?
Bromphenol Blue has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
Bromphenol Blue
Also known as: 5-19-03-00458, BRN 0061698, EINECS 204-086-2, 3',3'',5',5''-Tetrabromophenolsulfonephthalein, 3,3',5,5'-Tetrabromophenolsulfonphthalein (+3 more)
INCI: BROMPHENOL BLUE
Bromphenol Blue (CAS 115-39-9) is a cosmetic cosmetic ingredient functioning as RED. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 115-39-9 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
2,6-dibromo-4-[3-(3,5-dibromo-4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol
InChIKey
UDSAIICHUKSCKT-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Not established for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bromphenol Blue.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Skin Eye Respiratory Irritation
May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Biocide
Expert Verdict
Expert safety assessment and concern-level summary for Bromphenol Blue.
Known Synonyms
5-19-03-00458
BRN 0061698
EINECS 204-086-2
3',3'',5',5''-Tetrabromophenolsulfonephthalein
3,3',5,5'-Tetrabromophenolsulfonphthalein
Tetrabromphenol Blue
UNII-0R2969YC90
bromophenol blue, sultone form
Chemical Function
Biocide
Antioxidant
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BROMOPHENOL BLUE
ChEMBL ID
CHEMBL2103765
Max Phase
-1
Frequently Asked Questions
Is Bromphenol Blue allowed in the EU?
Bromphenol Blue EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bromphenol Blue do in cosmetics?
Bromphenol Blue functions as: RED. It is classified as a cosmetic ingredient in our database. CAS number: 115-39-9.
Is Bromphenol Blue used outside cosmetics?
Bromphenol Blue also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Bromphenol Blue compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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