What is the NOAEL for Tranexamic acid?
Tranexamic acid has 5 NOAEL studies in the database. The lowest reported value is 6T84R30KC1 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Tranexamic acid
Also known as: trans Amcha, 3-14-00-00868, trans-1-Aminomethylcyclohexane-4-carboxylic acid, trans-4-Aminomethylcyclohexane-1-carboxylic acid, BRN 2207452 (+15 more)
CAS 1197-18-8
Tranexamic acid (CAS 1197-18-8) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
10
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Tranexamic acid
CAS Number
1197-18-8
DTXSID
DTXSID3045350
Molecular Formula
C8H15NO2
InChI Key
GYDJEQRTZSCIOI-LJGSYFOKSA-N
Monoisotopic Mass
157.110279
Synonyms
trans Amcha3-14-00-00868trans-1-Aminomethylcyclohexane-4-carboxylic acidtrans-4-Aminomethylcyclohexane-1-carboxylic acidBRN 2207452CarxaminEINECS 214-818-2EmorhaltFrenolyseHexaprominHexatronNSC 291305
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
7 records
AstringentSoftener and conditionerPharmaceutical
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| Europe; pharmaceutical | Drinking Water Inspectorate | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 6T84R30KC1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6T84R30KC1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6T84R30KC1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6T84R30KC1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.97 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Tranexamic acid | 214-818-2 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
TRANEXAMIC ACID
ChEMBL Phase
4
Adverse Events
1992
Bioactivity
5
Frequently Asked Questions
What regulatory lists include Tranexamic acid?
Tranexamic acid appears on 6 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), Canada; Personal care; Substances in PCP - Canada (4/2014), active_ingredient; Australia, and 3 more. Source: EPA CPDat.
Is Tranexamic acid used in cosmetics?
Yes, Tranexamic acid is also indexed as a cosmetic ingredient under the name Tranexamic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Tranexamic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Tranexamic acid used outside industrial chemicals?
Tranexamic acid also appears in cosmetics, pharmaceutical databases.