What is the NOAEL for Octadecadienoic acid?
Octadecadienoic acid has 7 NOAEL studies in the database. The lowest reported value is G199I91G4B UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Octadecadienoic acid
Also known as: 9,11(or 10,12)-Octadecadienoic acid, Conjugated linoleic acid, CLA (conjugated linoleic acid), Tonalin, Nouracid HE 306 (+7 more)
CAS 121250-47-3
Octadecadienoic acid (CAS 121250-47-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Isomerized Safflower Acid →
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Octadecadienoic acid
CAS Number
121250-47-3
DTXSID
DTXSID1029091
Synonyms
9,11(or 10,12)-Octadecadienoic acidConjugated linoleic acidCLA (conjugated linoleic acid)TonalinNouracid HE 306Lutrell PureLutalinLuta-CLA 60CLA 80HGRCLA 80HGCLAUNII-70S2158RCI
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| G199I91G4B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G199I91G4B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G199I91G4B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G199I91G4B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3636 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 12628 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 15000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is Octadecadienoic acid used in cosmetics?
Yes, Octadecadienoic acid is also indexed as a cosmetic ingredient under the name Isomerized Safflower Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Octadecadienoic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Octadecadienoic acid used outside industrial chemicals?
Octadecadienoic acid also appears in cosmetics, cannabis databases.