What is the NOAEL for 4-Isopropylbenzaldehyde?
4-Isopropylbenzaldehyde has 7 NOAEL studies in the database. The lowest reported value is O0893NC35F UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
4-Isopropylbenzaldehyde
Also known as: Cuminaldehyde, 4-07-00-00723, BRN 0636547, EINECS 204-516-9, FEMA No. 2341 (+8 more)
CAS 122-03-2
4-Isopropylbenzaldehyde (CAS 122-03-2) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
4-Isopropylbenzaldehyde
CAS Number
122-03-2
DTXSID
DTXSID9021974
Molecular Formula
C10H12O
InChI Key
WTWBUQJHJGUZCY-UHFFFAOYSA-N
Monoisotopic Mass
148.088815
Synonyms
Cuminaldehyde4-07-00-00723BRN 0636547EINECS 204-516-9FEMA No. 2341UNII-O0893NC35F4-Isopropylbenzenecarboxylate4-propan-2-ylbenzaldehydeCuminal p-(1-methylethyl)benzaldehydeCuminic aldehydeP-Cuminic aldehydeP-Isopropyl benzaldehyde
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
14 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| O0893NC35F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O0893NC35F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O0893NC35F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O0893NC35F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 4-isopropylbenzaldehyde | 204-516-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CUMINALDEHYDE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 4-Isopropylbenzaldehyde?
4-Isopropylbenzaldehyde appears on 5 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 2 more. Source: EPA CPDat.
Is 4-Isopropylbenzaldehyde used in cosmetics?
Yes, 4-Isopropylbenzaldehyde is also indexed as a cosmetic ingredient under the name Cuminaldehyde. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-Isopropylbenzaldehyde come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 4-Isopropylbenzaldehyde used outside industrial chemicals?
4-Isopropylbenzaldehyde also appears in cosmetics, pharmaceutical, food safety, cannabis databases.