Is Cuminaldehyde safe in cosmetics?
Cuminaldehyde has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
MODERATE
Cosmetic Ingredient
Cuminaldehyde
Also known as: 4-07-00-00723, BRN 0636547, EINECS 204-516-9, FEMA No. 2341, UNII-O0893NC35F (+7 more)
INCI: CUMINALDEHYDE
Cuminaldehyde (CAS 122-03-2) is a cosmetic cosmetic ingredient functioning as Perfuming / Flavoring (FEMA GRAS 2341). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
Function
Perfuming / Flavoring (FEMA GRAS 2341)
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
4-propan-2-ylbenzaldehyde
InChIKey
WTWBUQJHJGUZCY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
FDA permitted in cosmetics; FEMA GRAS for flavoring; no specific FDA restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cuminaldehyde.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | 105 | 0 | 1181 | 1181 | non-sensitizer |
| HMT | - | 0 | 2592 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
IFRA Concentration Limits (12 Product Categories)
International Fragrance Association standards per product category. Restriction: Restriction. Effective: 2021-02-10.
| Category | Max % | Category | Max % |
|---|---|---|---|
| 1 (Lip products) | 0.02% | 7a (Deodorant – not spray) | 0.04% |
| 2 (Body spray) | 0.006% | 7b (Deodorant spray) | 0.04% |
| 3 (Body cream) | 0.02% | 8 (Face cream) | 0.0066% |
| 4 (Fine fragrance) | 0.079% | 9 (Soap) | 0.099% |
| 5a (Body lotion) | 0.02% | 10a (Household – non-spray) | 0.099% |
| 5b (Face cream leave-on) | 0.02% | 10b (Household – spray) | No Restriction% |
| 5c (Hand cream) | 0.02% | 11a (Intimate – leave-on) | 0.0066% |
| 5d (Baby cream) | 0.0066% | 11b (Intimate – rinse) | 0.0066% |
| 6 (Mouthwash) | 0.02% | 12 (Not for consumer exposure) | No Restriction% |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (6)
JECFA Number
868
Source: WHO/JECFA
JECFA Evaluation
CUMALDEHYDE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/73 | FAS 48-JECFA 57/227
Source: WHO/JECFA
JECFA Evaluation
CUMINAL | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/73 | FAS 48-JECFA 57/227
Source: WHO/JECFA
JECFA Evaluation
CUMINIC ALDEHYDE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/73 | FAS 48-JECFA 57/227
Source: WHO/JECFA
JECFA Evaluation
p-ISOPROPYLBENZALDEHYDE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/73 | FAS 48-JECFA 57/227
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (4)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Editorial summary
Preliminary editorial summary for Cuminaldehyde — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
epa_safer_alternative
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
4-07-00-00723
BRN 0636547
EINECS 204-516-9
FEMA No. 2341
UNII-O0893NC35F
4-Isopropylbenzenecarboxylate
4-propan-2-ylbenzaldehyde
Cuminal p-(1-methylethyl)benzaldehyde
Cuminic aldehyde
P-Cuminic aldehyde
P-Isopropyl benzaldehyde
p-Isopropyl-Benzaldehyde
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
SCIL (9/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CUMINALDEHYDE
ChEMBL ID
CHEMBL161577
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
CUMINALDEHYDE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Cuminaldehyde allowed in the EU?
Cuminaldehyde EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cuminaldehyde do in cosmetics?
Cuminaldehyde functions as: Perfuming / Flavoring (FEMA GRAS 2341). It is classified as a cosmetic ingredient in our database. CAS number: 122-03-2.
Is Cuminaldehyde used outside cosmetics?
Cuminaldehyde also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cuminaldehyde compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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