NOAEL Data REACH Registered Cosmetic Ingredient

3-Phenylpropyl acetate

Also known as: 1-Acetoxy-3-phenylpropane, 3-Acetoxy-1-phenylpropane, (3-Acetoxypropyl)benzene, BRN 0744307, EINECS 204-569-8 (+7 more)

CAS 122-72-5

3-Phenylpropyl acetate (CAS 122-72-5) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Hydrocinnamyl Acetate →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields
Name
3-Phenylpropyl acetate
CAS Number
122-72-5
DTXSID
DTXSID2047648
Molecular Formula
C11H14O2
InChI Key
JRJGKUTZNBZHNK-UHFFFAOYSA-N
Monoisotopic Mass
178.09938
Synonyms
1-Acetoxy-3-phenylpropane3-Acetoxy-1-phenylpropane(3-Acetoxypropyl)benzeneBRN 0744307EINECS 204-569-8FEMA No. 2890Hydrocinnamyl acetateNSC 4044533-Phenyl-1-propanol, acetatePhenylpropyl acetate3-Phenyl-1-propyl acetateUNII-AKW166708I

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
AKW166708IUNIIFDA UNII substance identifier--openFDA substances
AKW166708IUNIIFDA UNII substance identifier--openFDA substances
AKW166708IUNIIFDA UNII substance identifier--openFDA substances
AKW166708IUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
5184ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered3-phenylpropyl acetate204-569-8ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for 3-Phenylpropyl acetate?

3-Phenylpropyl acetate has 7 NOAEL studies in the database. The lowest reported value is AKW166708I UNII. Source: openFDA substances.

What regulatory lists include 3-Phenylpropyl acetate?

3-Phenylpropyl acetate appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is 3-Phenylpropyl acetate used in cosmetics?

Yes, 3-Phenylpropyl acetate is also indexed as a cosmetic ingredient under the name Hydrocinnamyl Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 3-Phenylpropyl acetate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is 3-Phenylpropyl acetate used outside industrial chemicals?

3-Phenylpropyl acetate also appears in cosmetics, food safety, cannabis databases.