Is Hydrocinnamyl Acetate safe in cosmetics?
Hydrocinnamyl Acetate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Hydrocinnamyl Acetate
Also known as: 1-Acetoxy-3-phenylpropane, 3-Acetoxy-1-phenylpropane, (3-Acetoxypropyl)benzene, BRN 0744307, EINECS 204-569-8 (+6 more)
Hydrocinnamyl Acetate (CAS 122-72-5) is a cosmetic cosmetic ingredient functioning as Flavouring and nutrient; Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 122-72-5 →
Auto-generated CPSR Part A draft with source citations
Function
Flavouring and nutrient; Fragrance
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-phenylpropyl acetate
InChIKey
JRJGKUTZNBZHNK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FEMA GRAS; FDA 21 CFR 172.515
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hydrocinnamyl Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 5184 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
638
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
3-PHENYLPROPYL ACETATE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/22 | FAS 46-JECFA 55/79
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
HYDROCINNAMYL ACETATE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/22 | FAS 46-JECFA 55/79
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Hydrocinnamyl Acetate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
1-Acetoxy-3-phenylpropane
3-Acetoxy-1-phenylpropane
(3-Acetoxypropyl)benzene
BRN 0744307
EINECS 204-569-8
FEMA No. 2890
NSC 404453
3-Phenyl-1-propanol, acetate
Phenylpropyl acetate
3-Phenyl-1-propyl acetate
UNII-AKW166708I
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
3-PHENYLPROPYL ACETATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Hydrocinnamyl Acetate allowed in the EU?
Hydrocinnamyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrocinnamyl Acetate do in cosmetics?
Hydrocinnamyl Acetate functions as: Flavouring and nutrient; Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 122-72-5.
Is Hydrocinnamyl Acetate used outside cosmetics?
Hydrocinnamyl Acetate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hydrocinnamyl Acetate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Acetaldehyde Diphenethyl Acetal
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Amyl Cinnamal
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Chemical family
Fragrance
Benzyl Isoamyl Ether
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Chemical family
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