NOAEL Data Cosmetic Ingredient

Saccharose acetate isobutyrate

Also known as: Isobutyric acid, hexaester with sucrose diacetate, Sucrose, diacetate hexaisobutyrate, Sucrose acetate isobutanoate, (2R,3R,4S,5R,6R)-2-((Acetyloxy)methyl)-6-(((2S,3S,4R,5R)-5-((acetyloxy)methyl)-3,4-bis((2-methylpropanoyl)oxy)-2-(((2-methylpropanoyl)oxy)methyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl tris(2-methylpropanoate), α-D-Glucopyranoside, 6-O-acetyl-1,3,4-tris-O-(2-methyl-1-oxopropyl)-β-D-fructofuranosyl, 6-acetate 2,3,4-tris(2-methylpropanoate) (+12 more)

CAS 126-13-6

Saccharose acetate isobutyrate (CAS 126-13-6) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Sucrose Acetate Isobutyrate →

SOURCE NOAEL studies
NOAEL studies
25
SOURCE Chemical inventory jurisdictions
Regulatory lists
1
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 22 fields
Name
Saccharose acetate isobutyrate
CAS Number
126-13-6
Molecular Formula
C40H62O19
InChI Key
ZNEBZIJCDDCNRC-SWTLDUCYSA-N
Monoisotopic Mass
846.38853
Synonyms
Isobutyric acid, hexaester with sucrose diacetateSucrose, diacetate hexaisobutyrateSucrose acetate isobutanoate(2R,3R,4S,5R,6R)-2-((Acetyloxy)methyl)-6-(((2S,3S,4R,5R)-5-((acetyloxy)methyl)-3,4-bis((2-methylpropanoyl)oxy)-2-(((2-methylpropanoyl)oxy)methyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl tris(2-methylpropanoate)α-D-Glucopyranoside, 6-O-acetyl-1,3,4-tris-O-(2-methyl-1-oxopropyl)-β-D-fructofuranosyl, 6-acetate 2,3,4-tris(2-methylpropanoate)SUCROSE ACETATE ISOBUTYRATESucrose acetoisobutyrateEINECS 204-771-6UNII-H5KI1C3YTVBinester SAABSAIBE 444

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records
Film formerPlasticizerSolventFlavouring and nutrientProcessing aids not otherwise specifiedSurface modifier

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 25 of 25 studies
ValueUnitEndpointRouteSpeciesSource
=20mg/kg bw/dayADI-ConsumersEFSA
H5KI1C3YTVUNIIFDA UNII substance identifier--openFDA substances
>5000mg/kg bwLD50oralRatNTP ICE acute oral
450mg/kg bw/dayLOAELoraldogCOSMOS DB
500mg/kg bw/dayLOAELoralratCOSMOS DB
150mg/kg bw/dayNOAELoraldogCOSMOS DB
190mg/kg bw/dayNOAELoralratCOSMOS DB
375mg/kg bw/dayNOAELoraldogCOSMOS DB
450mg/kg bw/dayNOAELoraldogCOSMOS DB
1200mg/kg bw/dayNOAELoralrabbitCOSMOS DB
1290mg/kg bw/dayNOAELoraldogCOSMOS DB
2000mg/kg bw/dayNOAELoralratCOSMOS DB
=2000mg/kg bw/dayNOAELoralRatEFSA
=2000mg/kg bw/dayNOAELoral: feedRatEFSA
2226mg/kg bw/dayNOAELoralratCOSMOS DB
2247mg/kg bw/dayNOAELoralratCOSMOS DB
2400mg/kg bw/dayNOAELoralmonkeyCOSMOS DB
2500mg/kg bw/dayNOAELoralratCOSMOS DB
2592mg/kg bw/dayNOAELoralratCOSMOS DB
2707mg/kg bw/dayNOAELoralratCOSMOS DB
4690mg/kg bw/dayNOAELoralratCOSMOS DB
5000mg/kg bw/dayNOAELoralratCOSMOS DB
5300mg/kg bw/dayNOAELoralratCOSMOS DB
5800mg/kg bw/dayNOAELoralmouseCOSMOS DB
1.000e+4mg/kg bw/dayNOAELoralmonkeyCOSMOS DB

Showing 25 of 25 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Rheology Modifier
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA 2 records

E444 — ADI: 20 mg/kg bw | FDA GRAS: FDA has no questions

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Saccharose acetate isobutyrate?

Saccharose acetate isobutyrate has 25 NOAEL studies in the database. The lowest reported value is 20 mg/kg bw/day in Consumers. Source: EFSA.

What regulatory lists include Saccharose acetate isobutyrate?

Saccharose acetate isobutyrate appears on 1 regulatory/inventory list including food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is Saccharose acetate isobutyrate used in cosmetics?

Yes, Saccharose acetate isobutyrate is also indexed as a cosmetic ingredient under the name Sucrose Acetate Isobutyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Saccharose acetate isobutyrate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Saccharose acetate isobutyrate used outside industrial chemicals?

Saccharose acetate isobutyrate also appears in cosmetics, food safety, cannabis databases.