NOAEL Data Cosmetic Ingredient

Sodium xylenesulfonate

Also known as: Benzenesulfonic acid, dimethyl-, sodium salt, Caswell No. 799A, Cyclophil sxs30, EINECS 215-090-9, EPA Pesticide Chemical Code 079019 (+4 more)

CAS 1300-72-7

Sodium xylenesulfonate (CAS 1300-72-7) is a chemical substance. Key regulatory status: 24 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC.

View cosmetic safety profile for Sodium Xylenesulfonate →

SOURCE noael studies public
NOAEL studies
45
SOURCE chemical inventory jurisdictions
Regulatory lists
24
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Sodium xylenesulfonate
CAS Number
1300-72-7
DTXSID
DTXSID3026302
Synonyms
Benzenesulfonic acid, dimethyl-, sodium saltCaswell No. 799ACyclophil sxs30EINECS 215-090-9EPA Pesticide Chemical Code 079019HydrotropeNCI-C55403Surco SXSUNII-G4LZF950UR

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records
FieldValue
Short-term EffectsThe substance is irritating to the eyes, skin and respiratory tract.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records
Solubility enhancerSurfactant (surface active agent)Wetting agent (non-aqueous)pH regulating agentThickening agentCleaning agentStabilizing agentEmulsifier

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 24 records
ListKeywordSource
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesCalifornia Department of Pesticide RegulationState of California
inert_ingredient; non_food_use; PesticidesEPACPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
SCIL (9/2019)USEPASafer Chemical Ingredients List
Indirect additives food contact (10/2018)FDAUnited States Food and Drug Administration (FDA)
Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; EuropeDanish EPADanish EPA
Cleaning products and household care; EuropeDanish EPADanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 45 of 45 studies
ValueUnitEndpointRouteSpeciesSource
G4LZF950URUNIIFDA UNII substance identifier--openFDA substances
G4LZF950URUNIIFDA UNII substance identifier--openFDA substances
G4LZF950URUNIIFDA UNII substance identifier--openFDA substances
G4LZF950URUNIIFDA UNII substance identifier--openFDA substances
=-mg/kg bw/dayLELdermalrat (fischer; Fischer 344)ToxRefDB_ToxRefDB_v3_pod.csv
=120mg/kg bw/dayLELdermalRatToxValDB_ToxRefDB
=120mg/kg bw/dayLELdermalrat (fischer; Fischer 344)ToxRefDB_ToxRefDB_v3_pod.csv
=170mg/kg bw/dayLELdermalMouseToxValDB_ToxRefDB
=170mg/kg bw/dayLELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
=440mg/kg bw/dayLELdermalMouseToxValDB_ToxRefDB
=440mg/kg bw/dayLELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
=727mg/kg bw/dayLELdermalMouseToxValDB_ToxRefDB
=727mg/kg bw/dayLELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
=1300mg/kg bw/dayLOAELdermalMouseToxValDB_ToxRefDB
=1300mg/kg bw/dayLOAELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
=1630mg/kg bw/dayLOAELdermalMouseToxValDB_ToxRefDB
=1630mg/kg bw/dayLOAELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
-unitlessModel Score--NTP_ICE_endocrine
>-mg/kg bw/dayNELdermalrat (fischer; Fischer 344)ToxRefDB_ToxRefDB_v3_pod.csv
=60mg/kg bw/dayNELdermalMouseToxValDB_ToxRefDB
=60mg/kg bw/dayNELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
=140mg/kg bw/dayNELdermalMouseToxValDB_ToxRefDB
=140mg/kg bw/dayNELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
=182mg/kg bw/dayNELdermalMouseToxValDB_ToxRefDB
=182mg/kg bw/dayNELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
=364mg/kg bw/dayNELdermalMouseToxValDB_ToxRefDB
=364mg/kg bw/dayNELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
>=60mg/kg bw/dayNOAELdermalRatToxValDB_ECHA_IUCLID
>=240mg/kg bw/dayNOAELdermalRatToxValDB_ECHA_IUCLID
>250mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
>=440mg/kg bw/dayNOAELdermalMouseToxValDB_ECHA_IUCLID
>=500mg/kg bw/dayNOAELdermalRatToxValDB_ECHA_IUCLID
=530mg/kg bw/dayNOAELdermalMouseToxValDB_ToxRefDB
=530mg/kg bw/dayNOAELdermalmouse (b6c3f1; B6C3F1)ToxRefDB_ToxRefDB_v3_pod.csv
>763mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
>=800mg/kg bw/dayNOAELdermalRatToxValDB_ECHA_IUCLID
<1000mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
>=1030mg/kg bw/dayNOAELdermalRatToxValDB_ECHA_IUCLID
>=1600mg/kg bw/dayNOAELdermalMouseToxValDB_ECHA_IUCLID
>=2000mg/kg bw/dayNOAELdermalMouseToxValDB_ECHA_IUCLID
<3534mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
>2439mg/kg bw/dayNOELoralMouseToxValDB_ECHA_IUCLID
-%Positive reactionDermalHumanNTP_ICE_skin_irritation
240mg/kgTop doseDermalRatNTP_ICE_cancer
727mg/kgTop doseDermalMouseNTP_ICE_cancer

Showing 45 of 45 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Sodium xylenesulfonate?

Sodium xylenesulfonate has 45 NOAEL studies in the database. The lowest reported value is G4LZF950UR UNII. Source: openFDA substances.

What regulatory lists include Sodium xylenesulfonate?

Sodium xylenesulfonate appears on 6 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, SCIL (9/2019), and 3 more. Source: EPA CPDat.

Is Sodium xylenesulfonate used in cosmetics?

Yes, Sodium xylenesulfonate is also indexed as a cosmetic ingredient under the name Sodium Xylenesulfonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Sodium xylenesulfonate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Sodium xylenesulfonate used outside industrial chemicals?

Sodium xylenesulfonate also appears in cosmetics databases.