Is Sodium Xylenesulfonate safe in cosmetics?
Sodium Xylenesulfonate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Sodium Xylenesulfonate
Also known as: Benzenesulfonic acid, dimethyl-, sodium salt, Caswell No. 799A, Cyclophil sxs30, EINECS 215-090-9, EPA Pesticide Chemical Code 079019 (+4 more)
INCI: SODIUM XYLENESULFONATE
Sodium Xylenesulfonate (CAS 1300-72-7) is a cosmetic cosmetic ingredient functioning as Surfactant – Hydrotrope (enhances solubility of substances in water). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 1300-72-7 →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant – Hydrotrope (enhances solubility of substances in water)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
sodium 3,4-dimethylbenzenesulfonate
InChIKey
QUCDWLYKDRVKMI-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA; manufacturer responsibility under MoCRA
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Xylenesulfonate.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
hair_care
{"hair_function": "cleansing", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "no", "cg_method_approved": "not-a-silicone", "silicone_type": "harsh", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "no", "color_safe": "neutral", "keratin_bond": "n…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Carcinogen Classification
Sodium Xylenesulfonate | TR-464: Toxicology and Carcinogenesis Studies of Technical Grade Sodium Xylenesulfonate (CASRN 1300-72-7) in F344/N Rats and B6C3F1 Mice (Dermal Studies) (1998 ) | 12/05/95 | No Evidence | No Evidence | No Evidence | No Evidence | Under the conditions of these 2-year dermal studies, there was no evidence of carcinogenic activity of sodium xylenesulfonate in male o
Source: NTP Technical Reports
ICSC Safety Card
1514
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Emulsifier
Solubility enhancer
Stabilizing agent
Surfactant (surface active agent)
Thickening agent
Viscosity modifier
Wetting agent (non-aqueous)
pH regulating agent
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Xylenesulfonate.
Regulatory Flags
epa_safer_alternative
Known Synonyms
Benzenesulfonic acid, dimethyl-, sodium salt
Caswell No. 799A
Cyclophil sxs30
EINECS 215-090-9
EPA Pesticide Chemical Code 079019
Hydrotrope
NCI-C55403
Surco SXS
UNII-G4LZF950UR
Chemical Function
Solubility enhancer
Surfactant (surface active agent)
Wetting agent (non-aqueous)
pH regulating agent
Thickening agent
Regulatory Lists
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Sodium Xylenesulfonate allowed in the EU?
Sodium Xylenesulfonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Xylenesulfonate do in cosmetics?
Sodium Xylenesulfonate functions as: Surfactant – Hydrotrope (enhances solubility of substances in water). It is classified as a cosmetic ingredient in our database. CAS number: 1300-72-7.
Is Sodium Xylenesulfonate used outside cosmetics?
Sodium Xylenesulfonate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sodium Xylenesulfonate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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