Danger GHS08GHS05GHS09 NOAEL Data Cosmetic Ingredient

Zeolites, AgZn

Also known as: Zeolites (synthetic), AgZn, AgZn zeolites, Zeolites, silver-zinc-exchanged, Bactekiller 102SD, Irgaguard B 5000 (+13 more)

CAS 130328-20-0

Zeolites, AgZn (CAS 130328-20-0) is a chemical substance with GHS signal word Danger; key hazard signal: H361d; H315; H318; H400; H410. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, SCCS.

View cosmetic safety profile for Ammonium Silver Zinc Aluminum Silicate →

SOURCE NOAEL studies
NOAEL studies
35
SOURCE Chemical inventory jurisdictions
Regulatory lists
2
SOURCE EU CLP Annex VI
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 20 fields
Name
Zeolites, AgZn
CAS Number
130328-20-0
Synonyms
Zeolites (synthetic), AgZnAgZn zeolitesZeolites, silver-zinc-exchangedBactekiller 102SDIrgaguard B 5000Bactekiller BM 102NSCSilver-zinc-exchanged zeolitesAgZn-exchanged zeolitesBactecide-NBactecide-SBactecideBactekiller BM 102NS-SB

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Repr. 2; Skin Irrit. 2; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1H361d; H315; H318; H400; H410GHS08; GHS05; GHS09Danger

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
AbsorbentPreservativeDeodorizer

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
active_ingredient; Europe; PesticidesCommission of the European CommunitiesCPCat
banned; Europe; Personal careEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 35 of 35 studies
ValueUnitEndpointRouteSpeciesSource
0.0045mg/kg bw/d-inhalationhumanRegulatory source
0.0065mg/kg bw/d-oralhumanRegulatory source
0.04--inhalation-Regulatory source
3.3--dermal-Regulatory source
3.5--dermal-Regulatory source
4.5--dermal-Regulatory source
5%-oralratRegulatory source
5--dermal-Regulatory source
31--dermal-Regulatory source
31.52mg/kg bw-oralhumanRegulatory source
275--dermal-Regulatory source
2017--dermal-Regulatory source
=0.0045mg/kg bw/dNOAELinhalationhumanSCCS Opinion
=0.0065mg/kg bw/dNOAELoralhumanSCCS Opinion
=0.04-NOAELinhalation-SCCS Opinion
=3.3-NOAELdermal-SCCS Opinion
=3.5-NOAELdermal-SCCS Opinion
=4.5-NOAELdermal-SCCS Opinion
=5%NOAELoralratSCCS Opinion
=5-NOAELdermal-SCCS Opinion
=20-NOAELoral-SCCS Opinion
=31-NOAELdermal-SCCS Opinion
=31.52mg/kg bwNOAELoralhumanSCCS Opinion
=50mg/kg bw/dayNOAEL-ratSCCS Opinion
=100mg/kg bw/dNOAEL-ratSCCS Opinion
=200mg/kg bw/dNOAELoralhumanSCCS Opinion
=250mg/kg bw/dNOAEL-dogSCCS Opinion
=275-NOAELdermal-SCCS Opinion
=1000mg/kg bwNOAELoral-SCCS Opinion
=1109mg/kg bwNOAELoralratSCCS Opinion
=2011-NOAELoral-SCCS Opinion
=2017-NOAELdermal-SCCS Opinion
100mg/kg bw/ddevelopmental toxicity-ratRegulatory source
0.0045mg/kg bw/drepeated dose toxicityinhalationratRegulatory source
50mg/kg bw/dayrepeated dose toxicity-ratRegulatory source

Showing 35 of 35 studies

SCCS Opinions

EU Scientific Committee opinions tied to the matched substance.

SOURCE SCCS Opinion 1 opinions
OpinionDateConclusionMax Conc.Concerns
SCCS/1650/2321 December 2023Safe with restrictions — safe only in spray deodorant and powder foundation at specified concentrationSpray deodorant: 1% (max 2.5% silver content); Powder foundation: 1% (max 2.5% silver content)Toxic for reproduction Cat. 2 (zinc); argyria risk (silver); inhalation concern for sprays addressed by insolubility of particles

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
1%
Category
Preservative
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for Zeolites, AgZn?

Zeolites, AgZn (CAS 130328-20-0) is classified under EU CLP Annex VI as Repr. 2; Skin Irrit. 2; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H361d; H315; H318; H400; H410. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Zeolites, AgZn?

Zeolites, AgZn has 35 NOAEL studies in the database. The lowest reported value is 0.0045 mg/kg bw/d via inhalation in human. Source: Regulatory source.

What regulatory lists include Zeolites, AgZn?

Zeolites, AgZn appears on 2 regulatory/inventory lists including active_ingredient; Europe; Pesticides, banned; Europe; Personal care. Source: EPA CPDat.

Is Zeolites, AgZn used in cosmetics?

Yes, Zeolites, AgZn is also indexed as a cosmetic ingredient under the name Ammonium Silver Zinc Aluminum Silicate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Zeolites, AgZn come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Zeolites, AgZn have different safety status in cosmetics vs industrial chemicals?

Zeolites, AgZn is prohibited in EU cosmetics at max 1% but has active industrial GHS classifications (H361d, H315, H318, H400, H410).

Is Zeolites, AgZn used outside industrial chemicals?

Zeolites, AgZn also appears in cosmetics databases.