Also known as: Zeolites (synthetic), AgZn, AgZn zeolites, Zeolites, silver-zinc-exchanged, Bactekiller 102SD, Irgaguard B 5000 (+14 more)
INCI: AMMONIUM SILVER ZINC ALUMINUM SILICATE
Ammonium Silver Zinc Aluminum Silicate (CAS 130328-20-0) is a cosmetic cosmetic ingredient functioning as Absorbent, deodorant, preservative. Reported NOAEL =0.0045 mg/kg bw/d in human (SCCS Opinion); EU Regulation 1223/2009 status: prohibited, max 1%; 2 safety opinions reviewed (SCCS Opinion). Industrial safety data is also available in the chemical safety database.
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Statusprohibited
EU Max Conc.1%
US US Statuspermitted
US NotesCIR reviewed under Silicates group — safe in the present practices of use and concentration when formulated to be non-irritating; insufficient data for inhalation of mined/natural-source variants
For full compliance data across multiple jurisdictions, use the
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Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ammonium Silver Zinc Aluminum Silicate.
Calculate MoS for your specific formulation with the
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Toxicological Studies
10 study endpoints found for Ammonium Silver Zinc Aluminum Silicate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
Endpoint
Value
Route
Species
Study Type
Source
NOAEL
=0.0045 mg/kg bw/d
inhalation
human
NOAEL study
SCCS Opinion
NOAEL
=0.0045 mg/kg bw/d
inhalation
human
NOAEL study
SCCS Opinion
NOAEL
=0.0045 mg/kg bw/d
inhalation
human
NOAEL study
SCCS Opinion
NOAEL
=0.0045 mg/kg bw/d
inhalation
human
NOAEL study
SCCS Opinion
NOAEL
=0.0065 mg/kg bw/d
oral
human
NOAEL study
SCCS Opinion
NOAEL
=0.0065 mg/kg bw/d
oral
human
NOAEL study
SCCS Opinion
NOAEL
=0.0065 mg/kg bw/d
oral
human
NOAEL study
SCCS Opinion
NOAEL
=0.0065 mg/kg bw/d
oral
human
NOAEL study
SCCS Opinion
NOAEL
=31.52 mg/kg bw
oral
human
NOAEL study
SCCS Opinion
NOAEL
=31.52 mg/kg bw
oral
human
NOAEL study
SCCS Opinion
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
SCCS OpinionSCCS/1650/2321 December 2023
Verdict: unknown
NOAEL: 50 mg/kg bw/d (not specified)
SCCS OpinionSCCS/1650/2321 December 2023
Verdict: unknown
NOAEL: 31.52 mg/kg bw (not specified)
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
H410Very toxic to aquatic life with long lasting effects
Specific Concentration Limits / M-factors
M = 100; M = 100
Inserted via ATP: ATP10
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1597
(EU) 2019/831
CMR:Reprotoxic Cat. 2()
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
India: Prohibited (GNRAS)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
AbsorbentDeodorizerPreservative
Regulatory List Membership (2)
EU Banned in CosmeticsEU CosIng Cosmetics Ingredient Database
Editorial summary
Preliminary editorial summary for Ammonium Silver Zinc Aluminum Silicate — not a computed safety verdict. See the sourced toxicological data above.
Public NOAEL study rows linked to Ammonium Silver Zinc Aluminum Silicate by CAS number or substance name.
Studies
36
Lowest NOAEL
0.0045
Highest NOAEL
1109
Units vary across source rows: mg/kg bw/d, mg/kg bw, mg/kg bw/day
SCCS Opinion
Known Synonyms
Zeolites (synthetic), AgZnAgZn zeolitesZeolites, silver-zinc-exchangedBactekiller 102SDIrgaguard B 5000Bactekiller BM 102NSCSilver-zinc-exchanged zeolitesAgZn-exchanged zeolitesBactecide-NBactecide-SBactecideBactekiller BM 102NS-SBAgION AK 80HZeomic ZA 10NZeomic AJ 10NZeomic AG 10NSilver zinc zeoliteZeolites, AgZnZeolites, synthetic, AgZn
Chemical Function
AbsorbentPreservativeDeodorizer
Regulatory Lists
active_ingredient; Europe; Pesticidesbanned; Europe; Personal care
Frequently Asked Questions
Is Ammonium Silver Zinc Aluminum Silicate safe in cosmetics?
Ammonium Silver Zinc Aluminum Silicate has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by SCCS Opinion.
Is Ammonium Silver Zinc Aluminum Silicate allowed in the EU?
Ammonium Silver Zinc Aluminum Silicate EU regulatory status: prohibited. Maximum allowed concentration: 1%. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Silver Zinc Aluminum Silicate do in cosmetics?
Ammonium Silver Zinc Aluminum Silicate functions as: Absorbent, deodorant, preservative. It is classified as a cosmetic ingredient in our database. CAS number: 130328-20-0.
What is the NOAEL for Ammonium Silver Zinc Aluminum Silicate?
The NOAEL (No Observed Adverse Effect Level) for Ammonium Silver Zinc Aluminum Silicate is =0.0045 mg/kg bw/d based on a NOAEL study study via inhalation route in human. A total of 10 study endpoints are available. Source: SCCS Opinion.
Compliance Tools
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