Moderate Cosmetic Ingredient NOAEL Data SCCS/CIR Reviewed

Ammonium Silver Zinc Aluminum Silicate

Also known as: Zeolites (synthetic), AgZn, AgZn zeolites, Zeolites, silver-zinc-exchanged, Bactekiller 102SD, Irgaguard B 5000 (+14 more)

INCI: AMMONIUM SILVER ZINC ALUMINUM SILICATE

Ammonium Silver Zinc Aluminum Silicate (CAS 130328-20-0) is a cosmetic cosmetic ingredient functioning as Absorbent, deodorant, preservative. Reported NOAEL =0.0045 mg/kg bw/d in human (SCCS_vision_codex); EU Regulation 1223/2009 status: prohibited, max 1%; 2 safety opinions reviewed (sccs). Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 130328-20-0 →

Auto-generated CPSR Part A draft with source citations
Function
Absorbent, deodorant, preservative
Safety Rating
MODERATE

Regulatory Status

EU EU Status prohibited
EU Max Conc. 1%
US US Status permitted
US Notes CIR reviewed under Silicates group — safe in the present practices of use and concentration when formulated to be non-irritating; insufficient data for inhalation of mined/natural-source variants

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Ammonium Silver Zinc Aluminum Silicate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Ammonium Silver Zinc Aluminum Silicate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =0.0045 mg/kg bw/d inhalation human NOAEL study SCCS_vision_codex
NOAEL =0.0045 mg/kg bw/d inhalation human NOAEL study SCCS_vision_codex
NOAEL =0.0045 mg/kg bw/d inhalation human NOAEL study SCCS_vision_codex
NOAEL =0.0045 mg/kg bw/d inhalation human NOAEL study SCCS_vision_codex
NOAEL =0.0065 mg/kg bw/d oral human NOAEL study SCCS_vision_codex
NOAEL =0.0065 mg/kg bw/d oral human NOAEL study SCCS_vision_codex
NOAEL =0.0065 mg/kg bw/d oral human NOAEL study SCCS_vision_codex
NOAEL =0.0065 mg/kg bw/d oral human NOAEL study SCCS_vision_codex
NOAEL =31.52 mg/kg bw oral human NOAEL study SCCS_vision_codex
NOAEL =31.52 mg/kg bw oral human NOAEL study SCCS_vision_codex

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

sccs SCCS/1650/23 21 December 2023
Verdict: unknown
NOAEL: 50 mg/kg bw/d (not specified)
sccs SCCS/1650/23 21 December 2023
Verdict: unknown
NOAEL: 31.52 mg/kg bw (not specified)

EU CLP Annex VI Harmonized Classification

Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.

Signal Word
Danger
Pictograms
Health HazardCorrosiveEnvironmental Hazard
Hazard Class and Category
Repr. 2; Skin Irrit. 2; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1
Hazard Statements
  • H361d
  • H315 Causes skin irritation
  • H318 Causes serious eye damage
  • H400 Very toxic to aquatic life
  • H410 Very toxic to aquatic life with long lasting effects
Specific Concentration Limits / M-factors
M = 100; M = 100

Inserted via ATP: ATP10

EU CosIng Annex Listing

European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.

Annex II — Prohibited
Ref: 1597
(EU) 2019/831
CMR: Reprotoxic Cat. 2()

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
India: Prohibited (GNRAS)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Absorbent Deodorizer Preservative
Regulatory List Membership (2)
EU Banned in Cosmetics EU CosIng Cosmetics Ingredient Database

Expert Verdict

Expert safety assessment and concern-level summary for Ammonium Silver Zinc Aluminum Silicate.

Regulatory Flags

preservative eu_banned_cosmetics eu_cosing_listed

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Ammonium Silver Zinc Aluminum Silicate by CAS number or substance name.

Studies
36
Lowest NOAEL
0.0045
Highest NOAEL
1109

Units vary across source rows: mg/kg bw/d, mg/kg bw/day, mg/kg bw

SCCS_vision_codex

Known Synonyms

Zeolites (synthetic), AgZn AgZn zeolites Zeolites, silver-zinc-exchanged Bactekiller 102SD Irgaguard B 5000 Bactekiller BM 102NSC Silver-zinc-exchanged zeolites AgZn-exchanged zeolites Bactecide-N Bactecide-S Bactecide Bactekiller BM 102NS-SB AgION AK 80H Zeomic ZA 10N Zeomic AJ 10N Zeomic AG 10N Silver zinc zeolite Zeolites, AgZn Zeolites, synthetic, AgZn

Chemical Function

Absorbent Preservative Deodorizer

Regulatory Lists

active_ingredient; Europe; Pesticides banned; Europe; Personal care

Frequently Asked Questions

Is Ammonium Silver Zinc Aluminum Silicate safe in cosmetics?

Ammonium Silver Zinc Aluminum Silicate has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by sccs.

Is Ammonium Silver Zinc Aluminum Silicate allowed in the EU?

Ammonium Silver Zinc Aluminum Silicate EU regulatory status: prohibited. Maximum allowed concentration: 1%. This is based on EU Regulation 1223/2009 and its amendments.

What does Ammonium Silver Zinc Aluminum Silicate do in cosmetics?

Ammonium Silver Zinc Aluminum Silicate functions as: Absorbent, deodorant, preservative. It is classified as a cosmetic ingredient in our database. CAS number: 130328-20-0.

What is the NOAEL for Ammonium Silver Zinc Aluminum Silicate?

The NOAEL (No Observed Adverse Effect Level) for Ammonium Silver Zinc Aluminum Silicate is =0.0045 mg/kg bw/d based on a NOAEL study study via inhalation route in human. A total of 10 study endpoints are available. Source: SCCS_vision_codex.

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