Danger GHS06GHS05GHS09 NOAEL Data REACH Registered Cosmetic Ingredient

Disodium sulfide

Also known as: Sodium sulfide (Na2S), EC No.: 215-211-5, EINECS 215-211-5, Sodium sulfide, anhydrous, Sodium sulfuret (+2 more)

CAS 1313-82-2

Disodium sulfide (CAS 1313-82-2) is a chemical substance with GHS signal word Danger; key hazard signal: H311; H302; H314; H400. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.

View cosmetic safety profile for Sodium Sulfide →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields
Name
Disodium sulfide
CAS Number
1313-82-2
DTXSID
DTXSID0029636
Molecular Formula
2Na.S
InChI Key
GRVFOGOEDUUMBP-UHFFFAOYSA-N
Monoisotopic Mass
77.95161
Synonyms
Sodium sulfide (Na2S)EC No.: 215-211-5EINECS 215-211-5Sodium sulfide, anhydrousSodium sulfuretUNII-YGR27ZW0Y7215-211-5

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Acute Tox. 3 *; Acute Tox. 4 *; Skin Corr. 1B; Aquatic Acute 1H311; H302; H314; H400GHS06; GHS05; GHS09Danger

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records
FieldValue
Short-term EffectsThe substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion.
Routes of ExposureThe substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Depilatory

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
Canada; consumer_product; Substances in Products - Canada (4/2014)Government of CanadaCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
=1.6mg/m3DNEL localinhalationHumanToxValDB_GESTIS_DNEL
=13.84mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
YGR27ZW0Y7UNIIFDA UNII substance identifier--openFDA substances
YGR27ZW0Y7UNIIFDA UNII substance identifier--openFDA substances
YGR27ZW0Y7UNIIFDA UNII substance identifier--openFDA substances
YGR27ZW0Y7UNIIFDA UNII substance identifier--openFDA substances
500mg/kg bw/dayNOAELoralratCOSMOS_DB

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredDisodium sulphide215-211-5ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL SODIUM SULFIDE
ChEMBL Phase
2
Adverse Events
4
Bioactivity
1
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Frequently Asked Questions

What is the GHS hazard classification for Disodium sulfide?

Disodium sulfide (CAS 1313-82-2) is classified under EU CLP Annex VI as Acute Tox. 3 *; Acute Tox. 4 *; Skin Corr. 1B; Aquatic Acute 1 with signal word Danger. Hazard statements: H311; H302; H314; H400. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Disodium sulfide?

Disodium sulfide has 7 NOAEL studies in the database. The lowest reported value is 1.6 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Disodium sulfide?

Disodium sulfide appears on 2 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Canada; consumer_product; Substances in Products - Canada (4/2014). Source: EPA CPDat.

Is Disodium sulfide used in cosmetics?

Yes, Disodium sulfide is also indexed as a cosmetic ingredient under the name Sodium Sulfide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Disodium sulfide come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Does Disodium sulfide have different safety status in cosmetics vs industrial chemicals?

Disodium sulfide is classified GHS Danger (H311, H302, H314, H400) in the chemicals database but is restricted in EU cosmetics.

Is Disodium sulfide used outside industrial chemicals?

Disodium sulfide also appears in cosmetics, pharmaceutical, food safety databases.