Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Sodium Sulfide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| dose_tested | 500 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
HIGHLY CAUSTIC — releases H₂S gas (toxic) in acidic conditions; causes severe skin burns; strict pH and concentration limits mandatory; "keep away from children" labeling required in EU; not for use on damaged/irritated skin; maximum contact time restrictions apply
Regulatory Flags
Frequently Asked Questions
Is Sodium Sulfide safe in cosmetics?
HIGHLY CAUSTIC — releases H₂S gas (toxic) in acidic conditions; causes severe skin burns; strict pH and concentration limits mandatory; "keep away from children" labeling required in EU; not for use on damaged/irritated skin; maximum contact time restrictions apply The EU classifies Sodium Sulfide as "restricted". Safety rating: POOR. 2 toxicological study endpoint(s) are available in our database.
Is Sodium Sulfide allowed in the EU?
Sodium Sulfide EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Sulfide do in cosmetics?
Sodium Sulfide functions as: Depilatory agent (hair removal). It is classified as a cosmetic ingredient in our database. CAS number: 1313-82-2.
What is the Margin of Safety for Sodium Sulfide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Sulfide?
The NOAEL (No Observed Adverse Effect Level) for Sodium Sulfide is 500 mg/kg bw/day based on a Chronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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