Is Sodium Sulfide safe in cosmetics?
Sodium Sulfide has a safety rating of "POOR" in our database. EU status: restricted. US status: permitted.
Sodium Sulfide
Also known as: Sodium sulfide (Na2S), EC No.: 215-211-5, EINECS 215-211-5, Sodium sulfide, anhydrous, Sodium sulfuret (+2 more)
INCI: SODIUM SULFIDE
Sodium Sulfide (CAS 1313-82-2) is a cosmetic cosmetic ingredient functioning as Depilatory agent (hair removal). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1313-82-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Sodium Sulfide is classified GHS Danger (H290, H301, H311, H302, H314, H318, H400, H251) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Depilatory agent (hair removal)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
disodium;sulfanide
InChIKey
VDQVEACBQKUUSU-UHFFFAOYSA-M
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Permitted with labeling requirements; classified as a depilatory active
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Sulfide.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion.
Routes of Exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
Acute ToxicityCorrosiveEnvironmental Hazard
Hazard Class and Category
Acute Tox. 3 *; Acute Tox. 4 *; Skin Corr. 1B; Aquatic Acute 1
Hazard Statements
- H311 Toxic in contact with skin
- H302 Harmful if swallowed
- H314 Causes severe skin burns and eye damage
- H400 Very toxic to aquatic life
Inserted via ATP: ATP01
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (2)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| IN | restricted | 2.0 | depilatory products only |
| BR | restricted | 2 | Depilatories only; pH up to 12.7 |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Depilatory
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Sulfide.
Regulatory Flags
fda_food_additive
Known Synonyms
Sodium sulfide (Na2S)
EC No.: 215-211-5
EINECS 215-211-5
Sodium sulfide, anhydrous
Sodium sulfuret
UNII-YGR27ZW0Y7
215-211-5
Chemical Function
Depilatory
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Canada; consumer_product; Substances in Products - Canada (4/2014)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
SODIUM SULFIDE
ChEMBL ID
CHEMBL2107611
Max Phase
2
Adverse Event Associations
4
Frequently Asked Questions
Is Sodium Sulfide allowed in the EU?
Sodium Sulfide EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Sulfide do in cosmetics?
Sodium Sulfide functions as: Depilatory agent (hair removal). It is classified as a cosmetic ingredient in our database. CAS number: 1313-82-2.
Is Sodium Sulfide used outside cosmetics?
Sodium Sulfide also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Sodium Sulfide have different safety status in cosmetics vs industrial chemicals?
Sodium Sulfide is classified GHS Danger (H290, H301, H311, H302, H314, H318, H400, H251) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check Sodium Sulfide compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Moderate
Chemical family
Antioxidant
Sodium Oxide
Moderate
Chemical family
Buffering (pH adjuster)
SODIUM (ASTROCARYUM VULGARE/EUTERPE OLERACEAE/PALM) FRUIT/(ASTROCARYUM VULGARE/PALM) KERNEL/(ASTROCARYUM MURUMURU/BABASSU/BERTHOLLETIA EXCELSA/CARAPA GUIANENSIS/COCOA/FEVILLEA TRILOBATA/PASSIFLORA EDULIS/THEOBROMA GRANDIFLORUM) SEEDATE
Good
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