What is the NOAEL for Celestolide?
Celestolide has 8 NOAEL studies in the database. The lowest reported value is E1HM68Q21P UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Celestolide
Also known as: Ethanone, 1-[6-(1,1-dimethylethyl)-2,3-dihydro-1,1-dimethyl-1H-inden-4-yl]-, 4-Acetyl-6-butyl-1,1-dimethylindane, 6-tert-Butyl-1,1-dimethyl-4-indanyl methyl ketone, 1-(6-(1,1-Dimethylethyl)-2,3-dihydro-1,1-dimethyl-1H-inden-4-yl)ethanone, EINECS 236-114-4 (+4 more)
CAS 13171-00-1
Celestolide (CAS 13171-00-1) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Celestolide is prohibited in EU cosmetics but has active industrial GHS classifications.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Celestolide
CAS Number
13171-00-1
DTXSID
DTXSID9044536
Molecular Formula
C17H24O
InChI Key
IKTHMQYJOWTSJO-UHFFFAOYSA-N
Monoisotopic Mass
244.182715
Synonyms
Ethanone, 1-[6-(1,1-dimethylethyl)-2,3-dihydro-1,1-dimethyl-1H-inden-4-yl]-4-Acetyl-6-butyl-1,1-dimethylindane6-tert-Butyl-1,1-dimethyl-4-indanyl methyl ketone1-(6-(1,1-Dimethylethyl)-2,3-dihydro-1,1-dimethyl-1H-inden-4-yl)ethanoneEINECS 236-114-4FEMA No. 3653Ketone, 6-tert-butyl-1,1-dimethyl-4-indanyl methylUNII-E1HM68Q21P1-(6-tert-Butyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethanone
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| E1HM68Q21P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E1HM68Q21P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E1HM68Q21P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E1HM68Q21P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 6-tert-butyl-1,1-dimethylindan-4-yl methyl ketone | 236-114-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3188960
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Celestolide?
Celestolide appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Celestolide used in cosmetics?
Yes, Celestolide is also indexed as a cosmetic ingredient under the name Celestolide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Celestolide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Celestolide have different safety status in cosmetics vs industrial chemicals?
Celestolide is prohibited in EU cosmetics but has active industrial GHS classifications.
Is Celestolide used outside industrial chemicals?
Celestolide also appears in cosmetics, pharmaceutical, cannabis databases.