What is the NOAEL for 2,4-Dichloro-3,5-dimethylphenol?
2,4-Dichloro-3,5-dimethylphenol has 6 NOAEL studies in the database. The lowest reported value is 51AC49OLT7 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,4-Dichloro-3,5-dimethylphenol
Also known as: Phenol, 2,4-dichloro-3,5-dimethyl-, Benzene, 2,4-dichloro-1,3-dimethyl-5-hydroxy-, Decasept, 2,4-Dichloro-M,5-xylenol, Dichlorxylenolum (+10 more)
CAS 133-53-9
2,4-Dichloro-3,5-dimethylphenol (CAS 133-53-9) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
2,4-Dichloro-3,5-dimethylphenol is classified GHS Danger (H302, H315, H318, H319, H312) in the chemicals database but is restricted in EU cosmetics at max 0.5%.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
2,4-Dichloro-3,5-dimethylphenol
CAS Number
133-53-9
DTXSID
DTXSID0041359
Molecular Formula
C8H8Cl2O
InChI Key
IYOLBFFHPZOQGW-UHFFFAOYSA-N
Monoisotopic Mass
189.99522
Synonyms
Phenol, 2,4-dichloro-3,5-dimethyl-Benzene, 2,4-dichloro-1,3-dimethyl-5-hydroxy-Decasept2,4-Dichloro-M,5-xylenolDichlorxylenolum3,5-Dimethyl-2,4-dichlorophenolEINECS 205-109-9NSC 9774OttacidePrinsyl3,5-Xylenol, 2,4-dichloro-Dichloroxylenolum
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
BiocideDeodorizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 51AC49OLT7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 51AC49OLT7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 51AC49OLT7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 51AC49OLT7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =7900 | mg/m3 | LEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,4-dichloro-3,5-xylenol | 205-109-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
0.5%
Category
Preservative
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
DICHLOROXYLENOL
ChEMBL Phase
2
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 2,4-Dichloro-3,5-dimethylphenol?
2,4-Dichloro-3,5-dimethylphenol appears on 2 regulatory/inventory lists including active_ingredient; Europe; Pesticides, pharmaceutical. Source: EPA CPDat.
Is 2,4-Dichloro-3,5-dimethylphenol used in cosmetics?
Yes, 2,4-Dichloro-3,5-dimethylphenol is also indexed as a cosmetic ingredient under the name Dichloro-m-Xylenol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,4-Dichloro-3,5-dimethylphenol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 2,4-Dichloro-3,5-dimethylphenol have different safety status in cosmetics vs industrial chemicals?
2,4-Dichloro-3,5-dimethylphenol is classified GHS Danger (H302, H315, H318, H319, H312) in the chemicals database but is restricted in EU cosmetics at max 0.5%.
Is 2,4-Dichloro-3,5-dimethylphenol used outside industrial chemicals?
2,4-Dichloro-3,5-dimethylphenol also appears in cosmetics, pharmaceutical databases.