Is Dichloro-m-Xylenol safe in cosmetics?
Dichloro-m-Xylenol has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Dichloro-m-Xylenol
Also known as: Phenol, 2,4-dichloro-3,5-dimethyl-, Benzene, 2,4-dichloro-1,3-dimethyl-5-hydroxy-, Decasept, 2,4-Dichloro-M,5-xylenol, Dichlorxylenolum (+10 more)
INCI: DICHLORO-M-XYLENOL
Dichloro-m-Xylenol (CAS 133-53-9) is a cosmetic cosmetic ingredient functioning as Antimicrobial / preservative. EU Regulation 1223/2009 status: restricted, max 0.5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 133-53-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Dichloro-m-Xylenol is classified GHS Danger (H302, H315, H318, H319, H312) in the chemicals database but is restricted in EU cosmetics at max 0.5%.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antimicrobial / preservative
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2,4-dichloro-3,5-dimethylphenol
InChIKey
IYOLBFFHPZOQGW-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.5%
US US Status
permitted
US Notes
Permitted — no specific CFR restriction; not on FDA prohibited list
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dichloro-m-Xylenol.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Deodorizer
Expert Verdict
Expert safety assessment and concern-level summary for Dichloro-m-Xylenol.
Regulatory Flags
preservative
Known Synonyms
Phenol, 2,4-dichloro-3,5-dimethyl-
Benzene, 2,4-dichloro-1,3-dimethyl-5-hydroxy-
Decasept
2,4-Dichloro-M,5-xylenol
Dichlorxylenolum
3,5-Dimethyl-2,4-dichlorophenol
EINECS 205-109-9
NSC 9774
Ottacide
Prinsyl
3,5-Xylenol, 2,4-dichloro-
Dichloroxylenolum
Dicloroxilenol
Dicloroxilenolo
UNII-51AC49OLT7
Chemical Function
Biocide
Deodorizer
Regulatory Lists
active_ingredient; Europe; Pesticides
pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
DICHLOROXYLENOL
ChEMBL ID
CHEMBL2104302
Max Phase
2
Frequently Asked Questions
Is Dichloro-m-Xylenol allowed in the EU?
Dichloro-m-Xylenol EU regulatory status: restricted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Dichloro-m-Xylenol do in cosmetics?
Dichloro-m-Xylenol functions as: Antimicrobial / preservative. It is classified as a cosmetic ingredient in our database. CAS number: 133-53-9.
Is Dichloro-m-Xylenol used outside cosmetics?
Dichloro-m-Xylenol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Dichloro-m-Xylenol have different safety status in cosmetics vs industrial chemicals?
Dichloro-m-Xylenol is classified GHS Danger (H302, H315, H318, H319, H312) in the chemicals database but is restricted in EU cosmetics at max 0.5%.
Compliance Tools
Check Dichloro-m-Xylenol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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