Dichloro-m-Xylenol

INCI: DICHLORO-M-XYLENOL

CAS Number
133-53-9
Function
Antimicrobial / preservative
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.5%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction; not on FDA prohibited list

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Chlorinated phenol with environmental persistence concern. Must stay within Annex V concentration limits. Not for use in oral products without specific assessment.

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Concern Level: Moderate

Regulatory Flags

preservative

Frequently Asked Questions

Is Dichloro-m-Xylenol safe in cosmetics?

Chlorinated phenol with environmental persistence concern. Must stay within Annex V concentration limits. Not for use in oral products without specific assessment. The EU classifies Dichloro-m-Xylenol as "restricted". Safety rating: MODERATE.

Is Dichloro-m-Xylenol allowed in the EU?

Dichloro-m-Xylenol EU regulatory status: restricted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Dichloro-m-Xylenol do in cosmetics?

Dichloro-m-Xylenol functions as: Antimicrobial / preservative. It is classified as a cosmetic ingredient in our database. CAS number: 133-53-9.

What is the Margin of Safety for Dichloro-m-Xylenol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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