What is the GHS hazard classification for 8-Hydroxyquinoline sulfate?
8-Hydroxyquinoline sulfate (CAS 134-31-6) is classified under EU CLP Annex VI as Acute Tox. 4 * with signal word Warning. Hazard statements: H302. Source: EU CLP Annex VI (ECHA).
Warning
GHS07
NOAEL Data
REACH Registered
Cosmetic Ingredient
8-Hydroxyquinoline sulfate
Also known as: 8-Quinolinol, sulfate (2:1), bis(8-hydroxyquinolinium) sulphate, sulfate de bis(8-hydroxyquinoleinium), Bis(8-hydroxychinolinium)sulfat, sulfato de bis(8-hidroxiquinolinio) (+15 more)
CAS 134-31-6
8-Hydroxyquinoline sulfate (CAS 134-31-6) is a chemical substance with GHS signal word Warning; key hazard signal: H302. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Warning
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
8-Hydroxyquinoline sulfate
CAS Number
134-31-6
DTXSID
DTXSID6025436
Molecular Formula
2C9H7NO.H2O4S
InChI Key
YYVFXSYQSOZCOQ-UHFFFAOYSA-N
Monoisotopic Mass
388.072907
Synonyms
8-Quinolinol, sulfate (2:1)bis(8-hydroxyquinolinium) sulphatesulfate de bis(8-hydroxyquinoleinium)Bis(8-hydroxychinolinium)sulfatsulfato de bis(8-hidroxiquinolinio)Caswell No. 719BCryptonolEINECS 205-137-1EPA Pesticide Chemical Code 059804KhinozolOctofenOxine sulfate
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
SOURCE
EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 4 * | H302 | GHS07 | Warning |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
BiocideEmulsifierChelating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 31.6050104317818 | uM | AC50 | - | - | NTP_ICE_endocrine |
| 28.5674646506914 | uM | ACC | - | - | NTP_ICE_endocrine |
| 61VUG75Y3P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61VUG75Y3P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61VUG75Y3P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61VUG75Y3P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 0.00897 | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Bis(8-hydroxyquinolinium) sulphate | 205-137-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
II/395
III/51
Category
Preservatives
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
OXYQUINOLINE SULFATE
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What is the NOAEL for 8-Hydroxyquinoline sulfate?
8-Hydroxyquinoline sulfate has 8 NOAEL studies in the database. The lowest reported value is 28.5674646506914 uM. Source: NTP_ICE_endocrine.
What regulatory lists include 8-Hydroxyquinoline sulfate?
8-Hydroxyquinoline sulfate appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, active_ingredient; Europe; Pesticides. Source: EPA CPDat.
Is 8-Hydroxyquinoline sulfate used in cosmetics?
Yes, 8-Hydroxyquinoline sulfate is also indexed as a cosmetic ingredient under the name OXYQUINOLINE SULFATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 8-Hydroxyquinoline sulfate come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 8-Hydroxyquinoline sulfate used outside industrial chemicals?
8-Hydroxyquinoline sulfate also appears in cosmetics, pharmaceutical, cannabis databases.