Is OXYQUINOLINE SULFATE safe in cosmetics?
OXYQUINOLINE SULFATE has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
OXYQUINOLINE SULFATE
Also known as: 8-Quinolinol, sulfate (2:1), bis(8-hydroxyquinolinium) sulphate, sulfate de bis(8-hydroxyquinoleinium), Bis(8-hydroxychinolinium)sulfat, sulfato de bis(8-hidroxiquinolinio) (+15 more)
OXYQUINOLINE SULFATE (CAS 134-31-6) is a cosmetic cosmetic ingredient functioning as Antimicrobial, Chelating. EU Regulation 1223/2009 status: restricted, max II/395 III/51. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 134-31-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
OXYQUINOLINE SULFATE is classified GHS Danger (H302, H317, H318, H361d) in the chemicals database but is restricted in EU cosmetics at max II/395 III/51.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antimicrobial, Chelating
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
bis(quinolin-8-ol);sulfuric acid
InChIKey
YYVFXSYQSOZCOQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
II/395
III/51
US US Status
restricted
US Notes
CIR: SQ - JACT 3(3):43-99, 1984
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Warning
Pictograms
Harmful / Irritant
Hazard Class and Category
Acute Tox. 4 *
Hazard Statements
- H302 Harmful if swallowed
Inserted via ATP: CLP00
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
Product type: (a) Stabilizer for hydrogen peroxide in rinse-off hair products (b) Stabilizer for hydrogen peroxide in leave-on hair products. Max: (a) (0,3 % as base) (b) (0,03 % as base).
BRIN Brazil/India Cosmetics
India: Restricted · max (a) (0,3 % as base) (b) (0,03 % as base)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Chelating agent
Emulsifier
Expert Verdict
Expert safety assessment and concern-level summary for OXYQUINOLINE SULFATE.
Regulatory Flags
cosing-sourced
eu-restricted
preservative
needs-enrichment
Known Synonyms
8-Quinolinol, sulfate (2:1)
bis(8-hydroxyquinolinium) sulphate
sulfate de bis(8-hydroxyquinoleinium)
Bis(8-hydroxychinolinium)sulfat
sulfato de bis(8-hidroxiquinolinio)
Caswell No. 719B
Cryptonol
EINECS 205-137-1
EPA Pesticide Chemical Code 059804
Khinozol
Octofen
Oxine sulfate
8-Quinolinol, hydrogen sulfate (2:1)
8-Quinolinol sulfate
Quinosol
Quinosol Extra
Solfato di 8-ossichinolina
Solvochin-Extra
Sunoxol
Superol
Chemical Function
Biocide
Emulsifier
Chelating agent
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
active_ingredient; Europe; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
OXYQUINOLINE SULFATE
ChEMBL ID
CHEMBL1697698
Max Phase
-1
Frequently Asked Questions
Is OXYQUINOLINE SULFATE allowed in the EU?
OXYQUINOLINE SULFATE EU regulatory status: restricted. Maximum allowed concentration: II/395 III/51. This is based on EU Regulation 1223/2009 and its amendments.
What does OXYQUINOLINE SULFATE do in cosmetics?
OXYQUINOLINE SULFATE functions as: Antimicrobial, Chelating. It is classified as a cosmetic ingredient in our database. CAS number: 134-31-6.
Is OXYQUINOLINE SULFATE used outside cosmetics?
OXYQUINOLINE SULFATE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does OXYQUINOLINE SULFATE have different safety status in cosmetics vs industrial chemicals?
OXYQUINOLINE SULFATE is classified GHS Danger (H302, H317, H318, H361d) in the chemicals database but is restricted in EU cosmetics at max II/395 III/51.
Compliance Tools
Check OXYQUINOLINE SULFATE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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