What is the NOAEL for Butyl benzoate?
Butyl benzoate has 13 NOAEL studies in the database. The lowest reported value is 864 uL/min/10^6 cells in Human. Source: NTP_ICE_adme_parameters.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Butyl benzoate
Also known as: 4-09-00-00290, Anthrapole AZ, BRN 1867073, Dai Cari XBN, EINECS 205-252-7 (+2 more)
CAS 136-60-7
Butyl benzoate (CAS 136-60-7) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
13
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Butyl benzoate
CAS Number
136-60-7
DTXSID
DTXSID8040694
Molecular Formula
C11H14O2
InChI Key
XSIFPSYPOVKYCO-UHFFFAOYSA-N
Monoisotopic Mass
178.09938
Synonyms
4-09-00-00290Anthrapole AZBRN 1867073Dai Cari XBNEINECS 205-252-7Butylester kyseliny benzooveUNII-1TGZ0D0O8I
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
PreservativeDeodorizerFlavouring and nutrientPlasticizerFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| artificial_saliva; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| artificial_sweat; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 864 | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| 1TGZ0D0O8I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1TGZ0D0O8I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1TGZ0D0O8I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1TGZ0D0O8I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.313 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 4050 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =735 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =5140 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| - | % | Positive reaction | Dermal | Human | NTP_ICE_skin_irritation |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 13 of 13 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Butyl benzoate | 205-252-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1868953
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Butyl benzoate?
Butyl benzoate appears on 6 regulatory/inventory lists including artificial_saliva; detected; emissions; Europe; Toys and children's products, artificial_sweat; detected; emissions; Europe; Toys and children's products, Indirect additives food contact (10/2018), and 3 more. Source: EPA CPDat.
Is Butyl benzoate used in cosmetics?
Yes, Butyl benzoate is also indexed as a cosmetic ingredient under the name Butyl Benzoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Butyl benzoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Butyl benzoate used outside industrial chemicals?
Butyl benzoate also appears in cosmetics, pharmaceutical, cannabis databases.