What is the NOAEL for 2-Heptylcyclopentanone?
2-Heptylcyclopentanone has 12 NOAEL studies in the database. The lowest reported value is 4984B2X8AH UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Heptylcyclopentanone
Also known as: Cyclopentanone, 2-heptyl-, Alismone, 4-07-00-00104, BRN 2043445, Cyclopentanone, 2-n-heptyl- (+8 more)
CAS 137-03-1
2-Heptylcyclopentanone (CAS 137-03-1) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
12
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
2-Heptylcyclopentanone
CAS Number
137-03-1
DTXSID
DTXSID8044547
Molecular Formula
C12H22O
InChI Key
PJXHBTZLHITWFX-UHFFFAOYSA-N
Monoisotopic Mass
182.167065
Synonyms
Cyclopentanone, 2-heptyl-Alismone4-07-00-00104BRN 2043445Cyclopentanone, 2-n-heptyl-EINECS 205-273-1alpha-Heptyl cyclopentanone2-n-Heptyl cyclopentanonealpha-Heptylcyclopentanone2-n-Heptylcyclopentanone2-Heptylcyclopentan-1-oneNSC 78468
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
12 records
DeodorizerFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 12 of 12 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 4984B2X8AH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4984B2X8AH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4984B2X8AH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4984B2X8AH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 775 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 6480 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HESS |
| >=800 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_HESS |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 12 of 12 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-heptylcyclopentanone | 205-273-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185887
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 2-Heptylcyclopentanone?
2-Heptylcyclopentanone appears on 3 regulatory/inventory lists including SCIL (9/2019), IFRA Transparency, consumer_product. Source: EPA CPDat.
Is 2-Heptylcyclopentanone used in cosmetics?
Yes, 2-Heptylcyclopentanone is also indexed as a cosmetic ingredient under the name 2-Heptylcyclopentanone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Heptylcyclopentanone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Heptylcyclopentanone used outside industrial chemicals?
2-Heptylcyclopentanone also appears in cosmetics, pharmaceutical databases.