Warning GHS02GHS07 NOAEL Data IARC Group 3 REACH Registered Cosmetic Ingredient

Butyl acrylate

Also known as: n-Butyl acrylate, 2-Propenoic acid, butyl ester, ACRYLATE, BUTYL, ACRYLIC ACID, BUTYL ESTER, PROP-2-ENOATE, BUTYL (+13 more)

CAS 141-32-2

Butyl acrylate (CAS 141-32-2) is a chemical substance with GHS signal word Warning; key hazard signal: H226; H335; H315; H319; H317. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, IARC, ECHA REACH, ILO ICSC, OSHA, EPA TRI.

View cosmetic safety profile for Butyl Acrylate →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 24 fields

Name

Butyl acrylate

CAS Number

141-32-2

DTXSID

DTXSID6024676

Molecular Formula

C7H12O2

InChI Key

CQEYYJKEWSMYFG-UHFFFAOYSA-N

Monoisotopic Mass

128.08373

Synonyms

n-Butyl acrylate2-Propenoic acid, butyl esterACRYLATE, BUTYLACRYLIC ACID, BUTYL ESTERPROP-2-ENOATE, BUTYLUN 2348 (DOT)Butan-1-yl acrylateButyl propenoate4-02-00-01463BRN 1749970EINECS 205-480-7Butylester kyseliny akrylove

IARC Carcinogen Classification

Carcinogenic hazard classification from IARC monograph evaluations.

SOURCE IARC Monographs on the Identification of Carcinogenic Hazards to Humans 1 records

Group	Meaning	Evaluated	Volume
Group 3	Not classifiable	1998	39, Sup 7, 71

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Flam. Liq. 3; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1	H226; H335; H315; H319; H317	GHS02; GHS07	Warning

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records

Field	Value
Short-term Effects	The substance is irritating to the eyes, skin and respiratory tract. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.
Long-term Effects	Repeated or prolonged contact may cause skin sensitization.
Routes of Exposure	The substance can be absorbed into the body by inhalation and through the skin.

OSHA Exposure Limits

Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.

SOURCE OSHA / NIOSH / ACGIH occupational exposure limits 6 records

Agency	Metric	Value	ppm	mg/m3	Skin
NIOSH	TWA	10 ppm (55 mg/m³)	10	55	N
ACGIH	TWA	2 ppm [1996]	2	-	N
CAL/OSHA	STEL	2 ppm (11 mg/m³)	2	11	N
AIHA	ERPG-1	0.05 ppm	0.05	-	-
AIHA	ERPG-2	25 ppm	25	-	-
AIHA	ERPG-3	250 ppm	250	-	-

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 9 records

Binder

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 10 records

List	Keyword	Source
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
Indirect additives food contact (10/2018)	FDA	United States Food and Drug Administration (FDA)
Europe; nondetect; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA
Europe; nondetect; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA
drinking_water; Europe; manufacturing; plastic_additive	Belgaqua	CPCat
Cons electronics mech appliances and machinery; detected; Europe	Danish EPA	Danish EPA
Cons electronics mech appliances and machinery; detected; Europe	Danish EPA	Danish EPA
Cons electronics mech appliances and machinery; detected; Europe	Danish EPA	Danish EPA
Europe; nondetect; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA
Europe; nondetect; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 46 of 46 studies

Value	Unit	Endpoint	Route	Species	Source
227	ug/mL	CD54, EC200	Dermal	-	NTP_ICE_skin_sensitization
32	ug/mL	CD86, EC150	Dermal	-	NTP_ICE_skin_sensitization
184	ug/mL	CD86, EC150	Dermal	-	NTP_ICE_skin_sensitization
332	ug/mL	CV75	Dermal	-	NTP_ICE_skin_sensitization
=11	mg/m3	DNEL local	inhalation	Human	ToxValDB_GESTIS_DNEL
100	%	Depletion Cys	Dermal	-	NTP_ICE_skin_sensitization
85.1	%	Depletion Lys	Dermal	-	NTP_ICE_skin_sensitization
91.7	%	Depletion Lys	Dermal	-	NTP_ICE_skin_sensitization
92.55	%	Depletion Lys + Cys	Dermal	-	NTP_ICE_skin_sensitization
range13.27	uM	EC1.5	Dermal	-	NTP_ICE_skin_sensitization
37.74	uM	EC1.5	Dermal	-	NTP_ICE_skin_sensitization
11	%	EC3	Dermal	Mouse	NTP_ICE_skin_sensitization
20	%	EC3	Dermal	Mouse	NTP_ICE_skin_sensitization
24.4	%	EC3	Dermal	Mouse	NTP_ICE_skin_sensitization
705NM8U35V	UNII	FDA UNII substance identifier	-	-	openFDA substances
705NM8U35V	UNII	FDA UNII substance identifier	-	-	openFDA substances
705NM8U35V	UNII	FDA UNII substance identifier	-	-	openFDA substances
705NM8U35V	UNII	FDA UNII substance identifier	-	-	openFDA substances
3	IARC group	IARC carcinogenicity classification	-	-	IARC Monographs
3	IARC group	IARC carcinogenicity classification	-	-	IARC Monographs
3	IARC group	IARC carcinogenicity classification	-	-	IARC Monographs
3	unitless	IARC group	-	-	NTP_ICE_cancer
200.9	uM	IC50	Dermal	-	NTP_ICE_skin_sensitization
6.9	ratio	Imax	Dermal	-	NTP_ICE_skin_sensitization
>5.24	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
10	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
10.0063	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
10.3	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
11.2	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
11.2113	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
12.652	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
13.3	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
14.0665	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
14.3	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
14.3022	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
>23.04	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
<26.7	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
33.3	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
=900	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
=3143	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
=3730	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
=9050	mg/kg bw	LD50	oral	Rat (Male)	NTP_ICE_acute_oral
=89117.3	mg/m3	LEL	inhalation	Human	ToxValDB_DOE_Protective_Action_Criteria
=78.6329	mg/m3	LOAEL	inhalation	Rat	ToxValDB_EU_SCOEL
-	unitless	Model Score	-	-	NTP_ICE_endocrine
=0.2	mg/org	NOEL	dermal	Mouse	ToxValDB_ECOTOX

Showing 46 of 46 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Butyl acrylate	205-480-7	ECHA overview →

EPA Toxic Release Inventory (TRI)

TRI hazard and reporting flags for the matched chemical.

SOURCE EPA Toxics Release Inventory (TRI) chemical list 1 records

Chemical	Category	Flags
Butyl acrylate	-	-

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL1546388

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the GHS hazard classification for Butyl acrylate?

Butyl acrylate (CAS 141-32-2) is classified under EU CLP Annex VI as Flam. Liq. 3; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1 with signal word Warning. Hazard statements: H226; H335; H315; H319; H317. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Butyl acrylate?

Butyl acrylate has 46 NOAEL studies in the database. The lowest reported value is 0 unitless. Source: NTP_ICE_endocrine.

What regulatory lists include Butyl acrylate?

Butyl acrylate appears on 5 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Indirect additives food contact (10/2018), Europe; nondetect; Other direct contact consumer goods, and 2 more. Source: EPA CPDat.

Is Butyl acrylate a carcinogen according to IARC?

Butyl acrylate is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1998). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.

What are the occupational exposure limits for Butyl acrylate?

Occupational exposure limits for Butyl acrylate are set by NIOSH, ACGIH, CAL/OSHA. 6 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.

Is Butyl acrylate used in cosmetics?

Yes, Butyl acrylate is also indexed as a cosmetic ingredient under the name Butyl Acrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Butyl acrylate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Butyl acrylate used outside industrial chemicals?

Butyl acrylate also appears in cosmetics, pharmaceutical, cannabis databases.