Good Cosmetic Ingredient NOAEL Data GHS Classified

Butyl Acrylate

INCI: BUTYL ACRYLATE

CAS Number
141-32-2
Function
Film forming agent (used exclusively as polymerized monomer in acrylate copolymers; unreacted monomer is not appropriate for cosmetic use)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Requires residual monomer quantification; MoS must be calculated based on residual free monomer in final product

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Butyl Acrylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 84 mg/kg bw/day oral rat oral REACH
LOAEL 150 mg/kg bw/day oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.
Long-term Exposure Effects
Repeated or prolonged contact may cause skin sensitization.
Routes of Exposure
The substance can be absorbed into the body by inhalation and through the skin.

Expert Verdict

Butyl acrylate is permitted as a polymerized monomer in cosmetics when residual free monomer levels are controlled and quantified.

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Concern Level: Low

Frequently Asked Questions

Is Butyl Acrylate safe in cosmetics?

Butyl acrylate is permitted as a polymerized monomer in cosmetics when residual free monomer levels are controlled and quantified. The EU classifies Butyl Acrylate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Butyl Acrylate allowed in the EU?

Butyl Acrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Butyl Acrylate do in cosmetics?

Butyl Acrylate functions as: Film forming agent (used exclusively as polymerized monomer in acrylate copolymers; unreacted monomer is not appropriate for cosmetic use). It is classified as a cosmetic ingredient in our database. CAS number: 141-32-2.

What is the Margin of Safety for Butyl Acrylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Butyl Acrylate?

The NOAEL (No Observed Adverse Effect Level) for Butyl Acrylate is 84 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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